Parkinson’s disease-associated alterations of the gut microbiome predict disease-relevant changes in metabolic functions

摘要

Overview of the study approach and the key methods used. Relative abundances were derived from 16S rRNA gene sequences (the “ ” section) and used as an input for the personalised community modelling to simulate metabolite secretion profiles. Relative abundances and secretion profiles were statistically analysed to identify microbial or metabolic differences between PD patients and controls