Correlation between the numbers of rotation steps in the ATPase and proton-conducting domains of F- and V-ATPases

摘要

The two rotary motors of ATP synthase, F and F . The subunit composition of F and F in bacterial types is α β γδε and , respectively, where varies among species. F rotates the rotary shaft, composed of the γ and ε subunits (red) against the α β stator ring (blue). F rotates the oligomer ring of the -subunits (red) against the stator complex (blue) during proton translocation across the membrane. In the whole ATP synthase complex, the rotor complexes F and F form the common rotary shaft (red) and stator complexes (blue), which are connected via the peripheral stalk formed by the and δ subunits