Objective This study was undertaken to determine whether there is a c orrelatio n between neonatal birth weight and an estimated or dye-determined amniotic flu id volume. Study design A prospective observational study of women undergoing an amniocentesis and subsequent delivery within 72 hours. Amniotic fluid volume wa s estimated using the amniotic fluid index (AFI) and single deepest pocket techn ique and calculated by the dye-dilution technique. Results One hundred seventy -five women participated in the study. Linear regression modelling showed no si gnificant relationship between birth weight and amniotic fluid volume adjusted f or gestational age (P=.062). Similarly, there was no evidence of an association between birth weight and a dye determined amniotic fluid volume (P=.180), fixed cutoffs for the AFI (P=.224), percentiles for the AFI (P=.112), or fixed cutof fs for the single deepest pockets (P=.867). Conclusion Neonatal birth weight is not correlated with a dye-determined or ultrasound estimated amniotic fluid vol ume.
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