Non-alcoholic fatty liver disease in patients with inflammatory bowel disease might boost cardiovascular disease burden

摘要

Recent data suggest that the presence of inflammatory bowel disease (IBD) increases the odds for non-alcoholic fatty liver disease (NAFLD) almost by 4.5 times [ ], with the latter representing the most common hepatobiliary manifestation among IBD patients [ ]. Independent risk factors of hepatic steatosis in IBD patients include disease relapse rate, surgery for disease and its complications and extent of intestinal involvement [ ]. However, this association also encompasses several cardio-metabolic risk factors, such as type 2 diabetes, hypertension, insulin resistance, metabolic syndrome and obesity [ , ].