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Differential roles of M2 and M3 muscarinic receptor subtypes in modulation of bladder afferent activity in rats

机译：M2和M3毒蕈碱受体亚型在大鼠膀胱传入活性调节中的差异作用

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ObjectivesIt has been proposed that the urothelium modulates the activity of bladder afferent pathways. However, the differential roles of muscarinic acetylcholine receptor (mAChR) subtypes in local bladder afferent activation remain unclear. We investigated the effects of various mAChR antagonists including selective M2 and M3 mAChR antagonists on bladder overactivity.

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期刊名称 other
作者
Yoshihiro Matsumoto; Minoru Miyazato; Akira Furuta; Kazumasa Torimoto; Yoshihiko Hirao; Michael B. Chancellor; Naoki Yoshimura;
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作者单位

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年(卷),期 -1(75),4
年度 -1
页码 862–867
总页数 10
原文格式 PDF
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关键词
rat urinary bladder afferent pathways muscarinic receptor;

机译：大鼠;膀胱;传入途径;毒蕈碱受体;

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专利

1. Differential roles of M2 and M3 muscarinic receptor subtypes in modulation of bladder afferent activity in rats. [J] . Matsumoto Y, Miyazato M, Furuta A, Urology . 2010,第4期

机译：M2和M3毒蕈碱受体亚型在大鼠膀胱传入活动调节中的不同作用。
2. The role of M2 muscarinic receptor subtypes in mediating contraction of the pig bladder base after cyclic adenosine monophosphate elevation and/or selective M3 inactivation. [J] . Yamanishi Tomonori, Chapple ChristopherR, Yasuda Kosaku, The Journal of Urology . 2002,第1期

机译：M2毒蕈碱受体亚型在循环单磷酸腺苷升高和/或选择性M3失活后介导猪膀胱基础收缩中的作用。
3. Gender comparison of muscarinic receptor expression and function in rat and human urinary bladder: differential regulation of M2 and M3 receptors? [J] . Kories C, Czyborra C, Fetscher C, Naunyn-Schmiedeberg's Archives of Pharmacology . 2003,第5期

机译：大鼠和人膀胱中毒蕈碱受体表达和功能的性别比较：M2和M3受体的差异调节？
4. Differential Role of Spinal Prostaglandin Receptor Subtypes EP1-EP4 in Rats with Normal and Inflamed Knee Joints [C] . Andrea Ebersberger, Karl-Jurgen Bar, Philipp Teschner, World Congress on Pain . 2003

机译：脊髓前列腺素受体亚型EP1-EP4在正常和发炎膝关节大鼠中的差异作用
5. The role of the M2 muscarinic receptor in maintaining urinary bladder function in a streptozotocin model of diabetes. [D] . Pak, Kirk Jihyon. 2010

机译：在糖尿病的链脲佐菌素模型中，M2毒蕈碱受体在维持膀胱功能中的作用。
6. ROLE OF M2 AND M3 MUSCARINIC ACETYLCHOLINE RECEPTOR SUBTYPES IN ACTIVATION OF BLADDER AFFERENT PATHWAYS IN SPINAL CORD INJURED RATS [O] . Y Matsumoto, M Miyazato, H Yokoyama, -1

机译：M2和M3毒蕈碱乙酰胆碱受体亚型在脊髓损伤大鼠膀胱传入途径中的作用
7. Differential Roles of M2 and M3 Muscarinic Receptor Subtypes in Modulation of Bladder Afferent Activity in Rats [O] . Yoshihiro Matsumoto, Minoru Miyazato, Akira Furuta, 2010

机译：M2和M3毒蕈碱受体亚型在大鼠膀胱传入活性调节中的差异作用
8. Differential Allosteric Effects of 8-(n,n-Diethylamine) Octyl-3,4,5-Trimethoxybenzoate-HC1(TMB-8) on Muscarinic Receptor Subtypes. [R] . Gordon, R. K., Chiang, P. K. 1989

机译：8-（n，n-二乙胺）辛基-3,4,5-三甲氧基苯甲酸盐-HCl（TmB-8）对毒蕈碱受体亚型的差异变构效应。

Differential roles of M2 and M3 muscarinic receptor subtypes in modulation of bladder afferent activity in rats

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