Pd(0)-Catalyzed Sequential Heck Reaction/C–H Activation/Amination with Diaziridinone: A Facile Approach to Indolines

摘要

Indolines are important moieties present in various biologically significant molecules and have attracted considerable attention in synthetic chemistry. This paper describes a sequential Heck reaction/C–H activation/amination process to form indoline with di-tert-butyldiaziridinone. The reaction process likely proceeds via a pallada(II)cycle, which is converted to an indoline by oxidative addition to the diaziridinone and subsequent double C–N bond formation.