Phase advancing human circadian rhythms with morning bright light afternoon melatonin and gradually shifted sleep: can we reduce morning bright light duration?

摘要

OBJECTIVEEfficient treatments to phase advance human circadian rhythms are needed to attenuate circadian misalignment and the associated negative health outcomes that accompany early morning shift work, early school start times, jet lag, and delayed sleep phase disorder. This study compared three morning bright light exposure patterns from a single light box (to mimic home treatment) in combination with afternoon melatonin.