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Efficacy and harms of direct oral anticoagulants in the elderly for stroke prevention in atrial fibrillation and secondary prevention of venous thromboembolism: systematic review and meta-analysis

机译：老年人直接口服抗凝剂在预防房颤和继发预防静脉血栓栓塞中的功效和危害：系统评价和荟萃分析

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摘要

BackgroundEvidence regarding use of direct oral anticoagulants (DOACs) in the elderly, particularly bleeding risks, is unclear despite the presence of greater comorbidities, polypharmacy and altered pharmacokinetics in this age group.

机译：背景技术尽管该年龄段存在合并症，多药治疗和药代动力学改变，但有关老年人使用直接口服抗凝剂（DOAC）的证据，尤其是出血风险尚不清楚。

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期刊名称 other
作者
Manuj Sharma; Victoria R Cornelius; Jignesh P Patel; J Graham Davies; Mariam Molokhia;
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作者单位

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年(卷),期 -1(132),3
年度 -1
页码 194–204
总页数 22
原文格式 PDF
正文语种
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关键词
elderly anticoagulant bleeding atrial fibrillation venous thromboembolism;

机译：老年人;抗凝剂;出血;房颤;静脉血栓栓塞;

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专利

1. Efficacy and Harms of Direct Oral Anticoagulants in the Elderly for Stroke Prevention in Atrial Fibrillation and Secondary Prevention of Venous Thromboembolism Systematic Review and Meta-Analysis [J] . Sharma Manuj, Cornelius Victoria R., Patel Jignesh P., Circulation: An Official Journal of the American Heart Association . 2015,第3期

机译：老年人直接口服抗凝剂对房颤预防卒中和静脉血栓栓塞的二级预防的功效和危害系统评价和荟萃分析
2. Over 1-year efficacy and safety of left atrial appendage occlusion versus novel oral anticoagulants for stroke prevention in atrial fibrillation: A systematic review and meta-analysis of randomized controlled trials and observational studies [J] . Li Xin, Wen Song-Nan, Li Song-Nan, Heart rhythm: the official journal of the Heart Rhythm Society . 2016,第6期

机译：左心耳闭塞与新型口服抗凝剂在房颤预防中风中的一年以上疗效和安全性：随机对照试验和观察性研究的系统评价和荟萃分析
3. Re: 'Efficacy and Safety of the New Oral Anticoagulants Dabigatran, Rivaroxaban, Apixaban, and Edoxaban in the Treatment and Secondary Prevention of Venous Thromboembolism: A Systematic Review and Meta-analysis of Phase III Trials'- Key Learning Points for Surgeons [J] . Hurst K. V., Lee R., Milosevic I., European journal of vascular and endovascular surgery: the official journal of the European Society for Vascular Surgery . 2015,第1期

机译：回复：“新型口服抗凝药达比加群，利伐沙班，阿哌沙班和埃多沙班在静脉血栓栓塞的治疗和二级预防中的功效和安全性：III期临床试验的系统评价和荟萃分析”-外科医生的主要学习重点
4. Evaluation of compliance with recommendations of prevention of thromboembolism in atrial fibrillation in the elderly, by data reuse of electronic health records [C] . Laurie FERRET, Jean-Baptiste BEUSCART, Gregoire FICHEUR, Medical Informatics in Europe Conference. . 2015

机译：通过电子健康记录的数据重用评估遵守预防老年心房颤动的血栓栓塞建议的建议
5. Cost effectiveness of warfarin in anticoagulant clinic after introduction of dabigatran for stroke prevention in atrial fibrillation patients in the United States [D] . Alhazami, Mai S. 2015

机译：在美国引入达比加群后预防心房颤动患者中风后华法林在抗凝临床中的成本效益
6. Oral anticoagulants for primary prevention treatment and secondary prevention of venous thromboembolic disease and for prevention of stroke in atrial fibrillation: systematic review network meta-analysis and cost-effectiveness analysis. [O] . Jonathan Ac Sterne, Pritesh N Bodalia, Peter A Bryden, -1

机译：口服抗凝剂用于静脉血栓栓塞性疾病的一级预防治疗和二级预防以及在房颤中预防中风：系统评价网络荟萃分析和成本效益分析。
7. Efficacy and Harms of Direct Oral Anticoagulants in the Elderly for Stroke Prevention in Atrial Fibrillation and Secondary Prevention of Venous Thromboembolism: Systematic Review and Meta-Analysis [O] . Sharma, Manuj, Cornelius, Victoria R., Patel, Jignesh P, 2015

机译：老年人直接口服抗凝药预防房颤和继发预防静脉血栓栓塞的疗效和危害：系统评价和荟萃分析

Efficacy and harms of direct oral anticoagulants in the elderly for stroke prevention in atrial fibrillation and secondary prevention of venous thromboembolism: systematic review and meta-analysis

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