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An Integrated Prognostic Classifier for Stage I Lung Adenocarcinoma based on mRNA microRNA and DNA Methylation Biomarkers

机译：基于mRNAmicroRNA和DNA甲基化生物标记物的I期肺腺癌综合预后分类器

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IntroductionUp to 30% Stage I lung cancer patients suffer recurrence within 5 years of curative surgery. We sought to improve existing protein-coding gene and microRNA expression prognostic classifiers by incorporating epigenetic biomarkers.

机译：引言治愈性外科手术的5年内，高达30％的I期肺癌患者会复发。我们试图通过整合表观遗传生物标记来改善现有的蛋白质编码基因和microRNA表达的预后分类器。

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作者
Ana I. Robles; Eri Arai; Ewy A. Mathé; Hirokazu Okayama; Aaron J. Schetter; Derek Brown; David Petersen; Elise D. Bowman; Rintaro Noro; Judith A. Welsh; Daniel C. Edelman; Holly S. Stevenson; Yonghong Wang; Naoto Tsuchiya; Takashi Kohno; Vidar Skaug; Steen Mollerup; Aage Haugen; Paul S. Meltzer; Jun Yokota; Yae Kanai; Curtis C. Harris;
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年(卷),期 -1(10),7
年度 -1
页码 1037–1048
总页数 22
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专利

1. An Integrated Prognostic Classifier for Stage I Lung Adenocarcinoma Based on mRNA, microRNA, and DNA Methylation Biomarkers [J] . Robles Ana I., Arai Eri, Mathe Ewy A., Journal of thoracic oncology: official publication of the International Association for the Study of Lung Cancer . 2015,第7期

机译：基于mRNA，microRNA和DNA甲基化生物标记物的I期肺腺癌的综合预后分类器
2. A prognostic predictor panel with DNA methylation biomarkers for early-stage lung adenocarcinoma in Asian and Caucasian populations [J] . I-Ying Kuo, Jayu Jen, Lien-Huei Hsu, Journal of biomedical science. . 2016,第1期

机译：DNA甲基化生物标志物的预后预测专家组用于亚洲和高加索人群的早期肺腺癌
3. A prognostic predictor panel with DNA methylation biomarkers for early-stage lung adenocarcinoma in Asian and Caucasian populations [J] . I-Ying Kuo, Jayu Jen, Lien-Huei Hsu, Journal of biomedical science. . 2016,第1期

机译：DNA甲基化生物标志物的预后预测专家组用于亚洲和高加索人群的早期肺腺癌
4. Improved MicroRNA Biomarkers for Pathological Stages in Lung Adenocarcinoma via Clustering of Dysregulated MicroRNA-Target Associations [C] . Nhat Tran, Borzou Alipourfard, Vinay Abhyankar, Annual International Conference of the IEEE Engineering in Medicine and Biology Society . 2017

机译：通过群体聚类，改善了肺腺癌病理阶段的微血管生物标志物通过多孔的微小罗纳 - 目标关联
5. Development of DNA methylation based biomarkers for the early detection of squamous cell lung cancer [D] . Anglim, Paul P. 2008

机译：基于DNA甲基化的生物标记物的开发，用于早期检测鳞状细胞肺癌
6. A prognostic predictor panel with DNA methylation biomarkers for early-stage lung adenocarcinoma in Asian and Caucasian populations [O] . I-Ying Kuo, Jayu Jen, Lien-Huei Hsu, 2016

机译：DNA甲基化生物标志物的预后预测专家组用于亚洲和高加索人群的早期肺腺癌
7. An Integrated Prognostic Classifier for Stage I Lung Adenocarcinoma Based on mRNA, microRNA, and DNA Methylation Biomarkers [O] . Ana I. Robles, Eri Arai, Ewy A. Mathé, 2015

机译：基于mRNA，microRNA和DNA甲基化生物标志物的阶段I肺腺癌的综合预后分类器
8. Development of a Diagnostic Tool to Detect DNA Methylation Biomarkers for Early-Stage Lung Cancer. [R] . Yuan, C., Liu, J., Kim, S., 2015

机译：开发用于检测早期肺癌DNa甲基化生物标志物的诊断工具。

An Integrated Prognostic Classifier for Stage I Lung Adenocarcinoma based on mRNA microRNA and DNA Methylation Biomarkers

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