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ADHD Severity as it Relates to Comorbid Psychiatric Symptomatology in Children with Autism Spectrum Disorders (ASD)

机译:自闭症谱系障碍(ASD)儿童的多动症严重程度与共病的精神症状有关

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摘要

Comorbid diagnoses identified in pediatric samples have been correlated with a range of outcomes, including greater levels of emotional, behavioral, and educational impairment and the need for more intensive treatment. Given that previous research has documented high levels of comorbid Attention-Deficit/Hyperactivity Disorder (ADHD) in children with Autism Spectrum Disorders (ASD), this study closely examines the relationship between parent-reported ADHD symptoms (i.e., Conners' Parent Rating Scale, Revised [CPRS-R]) and the prevalence of additional comorbid psychiatric diagnoses in a pediatric ASD sample (n = 99). Regression analyses revealed that greater severity of ADHD symptomatology was significantly related to a greater number of comorbid psychiatric diagnoses, as identified using the Diagnostic Interview for Children and Adolescents, 4th Edition (DICA-IV). Additionally, more severe ADHD symptoms were also associated with higher levels of symptom severity on Child Behavior Checklist (CBCL) syndrome subscales. Interestingly, increasing severity of ASD symptomatology, as measured by the Autism Diagnostic Interview, Revised (ADI-R), was not associated with a higher prevalence of comorbid psychiatric diagnoses or CBCL syndrome severity. Our study concluded that higher levels of ADHD severity—not ASD severity—were associated with a higher prevalence of comorbid psychiatric symptomatology in school-age children with ASD. These findings may encourage clinicians to thoroughly assess ADHD symptomatology in ASD children to better inform treatment planning.
机译:儿科样本中确定的合并症诊断与一系列结果相关,包括更高水平的情感,行为和教育障碍以及需要更深入的治疗。鉴于先前的研究已经证明自闭症谱系障碍(ASD)儿童患有高水平的并发注意力缺陷/多动障碍(ADHD),因此本研究仔细检查了父母报告的ADHD症状之间的关系(即Conners的父母评分量表,修订版[CPRS-R])和小儿ASD样本中其他合并症精神病诊断的患病率(n = 99)。回归分析表明,多动症症状的严重程度与更多的合并症精神病学诊断显着相关,如《儿童和青少年诊断访谈》(第4版)所确定的那样。此外,在儿童行为检查表(CBCL)综合征子量表上,更严重的ADHD症状也与较高的症状严重程度相关。有趣的是,自闭症诊断访谈(修订版)(ADI-R)衡量,ASD症状的严重程度增加与合并精神病诊断或CBCL综合征严重程度的高发生率无关。我们的研究得出结论,较高水平的ADHD严重程度而非ASD严重程度与学龄儿童ASD合并症的精神症状发生率较高相关。这些发现可能鼓励临床医生彻底评估ASD儿童的ADHD症状,以更好地指导治疗计划。

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