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The effect of MDR1 C3435T polymorphism on the eradication rate of H. pylori infection in PPI-based triple therapy

机译：基于PPI的三联疗法中MDR1 C3435T基因多态性对幽门螺杆菌感染根除率的影响

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摘要

Background:Several studies have reported that multidrug resistance gene 1 (MDR1) C3435T polymorphism was associated with the rate of Helicobacter pylori (H. pylori) eradication in proton pump inhibitor (PPI)-based triple therapy. However, the conclusions were inconsistent. Therefore, this meta-analysis was conducted to evaluate the impact of MDR1 C3435T polymorphism on H. pylori eradication by PPI-based triple therapy.

机译：背景：多项研究报道，在基于质子泵抑制剂（PPI）的三联疗法中，多药耐药基因1（MDR1）C3435T多态性与幽门螺杆菌（H. pylori）根除的比率有关。但是，结论是不一致的。因此，进行了这项荟萃分析，以评估基于PPI的三联疗法对MDR1 C3435T多态性对幽门螺杆菌根除的影响。

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期刊名称 other
作者
Meng Li; Taijie Li; Shihui Guo; Hongjie Liang; Dunke Jiang;
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作者单位

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年(卷),期 -1(96),13
年度 -1
页码 e6489
总页数 8
原文格式 PDF
正文语种
中图分类
关键词
helicobacter pylori MDR1 meta-analysis polymorphism;

机译：幽门螺杆菌;MDR1;荟萃分析;多态性;

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专利

1. Effect of MDR1 C3435T polymorphism on cure rates of Helicobacter pylori infection by triple therapy with lansoprazole, amoxicillin and clarithromycin in relation to CYP 2C19 genotypes and 23S rRNA genotypes of H. pylori. [J] . Furuta T, Sugimoto M, Shirai N, Alimentary pharmacology & therapeutics. . 2007,第5期

机译：MDR1 C3435T多态性对兰索拉唑，阿莫西林和克拉霉素三联疗法与幽门螺杆菌CYP 2C19基因型和23S rRNA基因型的关系对幽门螺杆菌感染治愈率的影响。
2. Infection: Bismuth improves PPI-based triple therapy for H. pylori eradication. [J] . Malfertheiner P Nature reviews. Gastroenterology & hepatology . 2010,第10期

机译：感染：铋改善了根除幽门螺杆菌的基于PPI的三联疗法。
3. Successful eradication of Helicobacter pylori infection with vonoprazan-based triple therapy after failure of PPI-based triple therapy [J] . Kawashima Kousaku, Ishihara Shunji, Kinoshita Yoshikazu Digestive and liver disease: official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver . 2016,第6期

机译：基于PPI的三联疗法失败后，采用基于vonoprazan的三联疗法成功根除幽门螺杆菌感染
4. Optical modelling of the gastric tissue to optimize the phototherapy efficacy against H. pylori infection [C] . Giovanni Romano, Silvia Calusi, Alessio Gnerucci, Italian National Conference on Photonic Technologies . 2017

机译：胃组织的光学建模优化H.幽门螺杆菌感染的光疗疗效
5. Secondary analysis of effectivness of tinidazole-containing-quadruple eradication therapy in asymptomatic Helicobacter pylori infected children in El Paso [D] . Prieto-Jimenez, Carmen Aida 2010

机译：EL Pyliancational幽门螺杆菌幽门螺杆菌幽门术中含锡咪唑类含有四肢切除治疗的有效性的二次分析
6. Effects of CYP2C19 Loss-of-Function Variants on the Eradication of H. pylori Infection in Patients Treated with Proton Pump Inhibitor-Based Triple Therapy Regimens: A Meta-Analysis of Randomized Clinical Trials [O] . Hui-Lin Tang, Yan Li, Yong-Fang Hu, -1

机译：CYP2C19功能丧失变异对基于质子泵抑制剂的三联疗法治疗的患者根除幽门螺杆菌感染的影响：一项随机临床试验的荟萃分析
7. PGS8 COST-MINIMISATION ANALYSIS OF PPI-BASED TRIPLE THERAPY FOR THE ERADICATION OF HELICOBACTER PYLORI [O] . Plumb JM, Edwards SJ 2003

机译：基于PPI的三联疗法消灭幽门螺杆菌的PGS8成本最小化分析

The effect of MDR1 C3435T polymorphism on the eradication rate of H. pylori infection in PPI-based triple therapy

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