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Enhancing Photodynamic Therapy Through Resonance-Energy-Transfer Constructed Near InfraRed Photosensitized Nanoparticles

机译：通过共振能量转移构造的近红外光敏纳米粒子增强光动力疗法

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摘要

>Resonance energy transfer constructed NIR-absorbing BODIPY-based photosensitized dyad (>RET-BDP) nanoparticles are developed. These nanoparticles enable targeted photodynamic therapy upon application of low-power NIR LED light irradiation. This work provides a new concept for the design of biocompatible nanoparticles with significantly improved NIR sensitivity, which is key to PDT development.

机译：>共振能量转移构建的基于近红外吸收的基于BODIPY的光敏二元体（> RET-BDP ）纳米粒子。这些纳米粒子能够在应用低功率NIR LED光照射后进行有针对性的光动力疗法。这项工作为生物相容性纳米颗粒的设计提供了一个新的概念，该纳米颗粒具有显着提高的NIR敏感性，这是PDT开发的关键。

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期刊名称 other
作者
Ling Huang; Dr. Zhanjun Li; Dr. Yang Zhao; Jinyi Yang; Yucheng Yang; Aarushi Iris Pendharkar; Dr. Yuanwei Zhang; Sharon Kelmar; Prof. Liyong Chen; Prof. Wenting Wu; Prof. Jianzhang Zhao; Prof. Gang Han;
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年(卷),期 -1(29),28
年度 -1
页码 201604789
总页数 16
原文格式 PDF
正文语种
中图分类
关键词
bodipy near infrared nanoparticles resonance energy transfer photodynamic therapy;

机译：身体;近红外;纳米粒子;共振能量转移;光动力疗法;

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专利

1. Enhancing Photodynamic Therapy through Resonance Energy Transfer Constructed Near-Infrared Photosensitized Nanoparticles [J] . Huang Ling, Li Zhanjun, Zhao Yang, Advanced Materials . 2017,第28期

机译：通过共振能量转移构建近红外光敏纳米粒子增强光动力疗法。
2. Sharp pH-responsive mannose prodrug polypeptide nanoparticles encapsulating a photosensitizer for enhanced near infrared imaging-guided photodynamic therapy [J] . Yuan Pan, Ruan Zheng, Li Tuanwei, Journal of Materials Chemistry, B. materials for biology and medicine . 2019,第43期

机译：夏普响应甘露糖前药物多肽纳米粒子包封光敏剂以增强近红外成像引导的光动力治疗
3. Core-shell polymeric nanoparticles co-loaded with photosensitizer and organic dye for photodynamic therapy guided by fluorescence imaging in near and short-wave infrared spectral regions [J] . O. M. Chepurna, A. Yakovliev, R. Ziniuk, Journal of Nanobiotechnology . 2020,第1期

机译：核 - 壳聚合物纳米颗粒与光敏剂和有机染料共同加载用于光动力疗法，以近近和短波红外光谱区引导的荧光成像
4. Photosensitizer-loaded nanoparticles: a strategy to enhance the vascular occlusionin response to photodynamic therapy [C] . Angelica Vargas, Robert Gurny, Florence Delie Annual meeting exposition of the Controlled Release Society . 2005

机译：装载光敏剂的纳米颗粒：增强对光动力疗法的血管阻塞的策略
5. The effect of photodynamic therapy (PDT) on epidermal growth factor receptor and interleukin-6 cytokine signaling, and tyrosine kinase inhibitors enhance the efficacy of PDT by increasing intracellular accumulation of photosensitizers. [D] . Liu, Weiguo. 2005

机译：光动力疗法（PDT）对表皮生长因子受体和白介素6细胞因子信号转导的影响，酪氨酸激酶抑制剂通过增加光敏剂在细胞内的积累来增强PDT的功效。
6. Near-Infrared Light-Triggered Photodynamic Therapy and Apoptosis Using Upconversion Nanoparticles With Dual Photosensitizers [O] . Song Yeul Lee, Ruda Lee, Eunha Kim, 2020

机译：使用具有双重光敏剂的上转换纳米粒子进行近红外光触发的光动力疗法和细胞凋亡
7. Nanomedicine: Enhancing Photodynamic Therapy through Resonance Energy Transfer Constructed Near-Infrared Photosensitized Nanoparticles (Adv. Mater. 28/2017) [O] . Ling Huang, Zhanjun Li, Yang Zhao, 2017

机译：Nanomedicine：通过共振能量转移增强光动力学治疗，构建近红外光敏纳米粒子（ADV。Mater。28/2017）

Enhancing Photodynamic Therapy Through Resonance-Energy-Transfer Constructed Near InfraRed Photosensitized Nanoparticles

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