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Prevalence of Dyslipidemia and Lipid Goal Attainment in Statin-Treated Subjects From 3 Data Sources: A Retrospective Analysis

机译:从3个数据源中经他汀治疗的受试者中血脂异常的发生率和血脂目标的实现:回顾性分析

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摘要

BackgroundEvidence-based randomized clinical trials have shown significant benefit of statin treatment with regard to cardiovascular disease. In anticipation of the National Cholesterol Education Program Adult Treatment Panel IV guidelines, we wanted to assess the current state of lipid goal attainment in the high-risk secondary prevention population in the United States. The objectives of the study were to estimate the proportion of high-risk patients treated with statin monotherapy who achieved Adult Treatment Panel III–recommended low-density lipoprotein cholesterol (LDL-C) goals (<100 mg/dL; optional <70 mg/dL) as well as non–high-density lipoprotein cholesterol goals (<130 mg/dL; optional <100 mg/dL).
机译:背景基于证据的随机临床试验表明,他汀类药物治疗对心血管疾病有显着益处。根据美国国家胆固醇教育计划成人治疗小组IV指南的预期,我们希望评估美国高危二级预防人群中实现脂质目标的现状。该研究的目的是评估通过他汀类药物单药治疗的高危患者达到成人治疗小组III推荐的低密度脂蛋白胆固醇(LDL-C)目标的比例(<100 mg / dL;可选的<70 mg / dL)以及非高密度脂蛋白胆固醇目标(<130 mg / dL;可选的<100 mg / dL)。

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