Rate of viral load failure over time in people on ART in the UK Collaborative HIV Cohort (CHIC) study

摘要

IntroductionMost people achieve and maintain viral load (VL) suppression on first-line antiretroviral therapy (ART) but for a minority this does not happen. It is unclear whether those who have maintained VL suppression for several years will be able to continue to do so, or if rates of VL failure – due to poor adherence, ART interruption and/or resistance – remain at appreciable levels.