18 F-FDG PET standard uptake values of the normal pons in children: establishing a reference value for diffuse intrinsic pontine glioma

摘要

BackgroundPositron emission tomography (PET) scanning with [¹⁸ F]fluorodeoxyglucose (¹⁸ F-FDG) is a useful diagnostic and prediction tool in brain tumors, but its value in childhood diffuse intrinsic pontine glioma (DIPG) is still unclear. For interpretation of ¹⁸ F-FDG PET results in DIPG, uptake values of the normal pons of children of increasing ages are mandatory. The aim of this study was to determine ¹⁸ F-FDG standard uptake value ratios (SUVr) of the normal pons and to compare these to those of DIPG.