首页> 美国卫生研究院文献>Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease >Effects of the P‐Selectin Antagonist Inclacumab on Myocardial Damage After Percutaneous Coronary Intervention According to Timing of Infusion: Insights From the SELECT‐ACS Trial
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Effects of the P‐Selectin Antagonist Inclacumab on Myocardial Damage After Percutaneous Coronary Intervention According to Timing of Infusion: Insights From the SELECT‐ACS Trial

机译:P-Selectin拮抗剂Inclacumab对根据输注时间经皮冠状动脉介入治疗后心肌损伤的影响:SELECT-ACS试验的启示

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摘要

BackgroundThe Effects of the P‐Selectin Antagonist Inclacumab on Myocardial Damage After Percutaneous Coronary Intervention for Non‐ST‐Segment Elevation Myocardial Infarction (SELECT‐ACS) trial suggested beneficial effects of inclacumab, a monoclonal antibody directed against P‐selectin, on periprocedural myocardial damage. This study evaluated the effect of inclacumab on myocardial damage according to varying time intervals between study drug infusion and percutaneous coronary intervention (PCI).
机译:背景P-选择素拮抗剂Inclacumab对非ST段抬高型心肌梗死的经皮冠状动脉介入治疗后对心肌损害的影响表明,Inclacumab是针对P-选择素的单克隆抗体,对围手术期心肌有有益作用。 。这项研究根据研究药物输注和经皮冠状动脉介入治疗(PCI)之间不同的时间间隔评估了Inclacumab对心肌损伤的影响。

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