Impact of Multiplex Polymerase Chain Reaction Technology with Antimicrobial Stewardship Interventions in the Management of Patients with Positive Blood Cultures

摘要

BackgroundTraditional blood culture identification methods often lead to delayed time to optimal antimicrobial agents. This delay may increase morbidity and mortality. Rapid diagnostic tests decrease time to organism identification. The BioFire FilmArray®, a multiplex Polymerase Chain Reaction (mPCR) technology, was implemented at CHI Memorial in October 2016. We aimed to evaluate the tool’s blood culture identification panel in conjunction with antimicrobial stewardship (AS) on improving the management of patients with blood stream infections.