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Prevalence and Risk Factors of Carotid Plaque Among Middle-aged and Elderly Adults in Rural Tianjin China

机译:天津市农村中老年人的颈动脉斑块患病率及危险因素

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摘要

Carotid plaque (CP) is associated with cardiovascular and cerebrovascular events. However, population-based studies with a large sample are rare in China, particularly those in the low-income population. We aimed to determine the prevalence of CP and the associated risk factors in the rural areas of northern China. Between April 2014 and June 2014, we recruited 3789 residents aged ≥45 years. B-mode ultrasonography was performed to measure the extent of CP. The prevalence of CP was 40.3% overall, 47.1% in men, and 35.4% in women (P < 0.001). The prevalence of CP increased with increasing age (P < 0.001). The participants with CP were more likely to have hypertension, diabetes, high total cholesterol (TC) levels, and high low-density lipoprotein-cholesterol levels and be a current smoker; however, they were less likely to be obese. Multiple logistic regression analysis, adjusted for confounders, indicated that age, male sex, hypertension, diabetes, current smoking, and high LDL-C levels were the independent risk factors for CP. There was a lower risk of CP with alcohol consumption. The findings suggest that managing the conventional risk factors is crucial to reduce the burden of cardiovascular and cerebrovascular diseases in the low-income population in China.
机译:颈动脉斑块(CP)与心血管和脑血管事件相关。但是,在中国,尤其是在低收入人群中,很少进行基于人口的样本研究。我们旨在确定中国北方农村地区CP的患病率和相关的危险因素。在2014年4月至2014年6月期间,我们招募了3789名年龄≥45岁的居民。进行B型超声检查以测量CP程度。总体上,CP的患病率为40.3%,男性为47.1%,女性为35.4%(P <0.001)。 CP的患病率随着年龄的增长而增加(P <0.001)。患有CP的参与者更有可能患有高血压,糖尿病,高总胆固醇(TC)和高低密度脂蛋白胆固醇水平,并且是当前吸烟者;但是,他们不太可能肥胖。校正混杂因素的多元逻辑回归分析表明,年龄,男性,高血压,糖尿病,目前吸烟和高LDL-C水平是CP的独立危险因素。饮酒会降低CP的风险。研究结果表明,控制常规危险因素对于减轻中国低收入人群的心血管和脑血管疾病负担至关重要。

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