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Objective evaluation of size and shape of superficial foveal avascular zone in normal subjects by optical coherence tomography angiography

机译:光学相干断层扫描血管造影术客观评估正常受试者浅表黄斑中心凹血管区的大小和形状

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摘要

This study was conducted to investigate the size and shape of the foveal avascular zone (FAZ) determined by optical coherence tomography angiography (OCTA) and the relationship of the size and shape to the clinical findings in normal subjects. This was a cross-sectional study with seventy eyes of 70 volunteers. The size of the superficial FAZs were assessed by its area, length of perimeter, and Feret’s diameter, and the shape by the circularity, axial ratio, roundness, and solidity. The correlations between each parameter and the clinical findings were statistically determined. The coefficients of variation (CV) of the parameters of FAZ size were higher than that of the parameters of FAZ shape. The refractive error and axial length were significantly correlated with area-related factors. The central macular thickness (CMT) was significantly correlated with all parameters. Although the CMT was a critical factor that was significantly correlated with the size and shape characteristics of the FAZ, the shape might be a better factor for characterizing the FAZ than the size because of the low CV of shape-related factors and the characteristics are less affected by the other ocular factors.
机译:这项研究的目的是调查通过光学相干断层扫描血管造影(OCTA)确定的中央凹无血管区(FAZ)的大小和形状,以及大小和形状与正常受试者临床表现之间的关系。这是一项横断面研究,涉及70位志愿者的70眼。表面FAZ的大小通过其面积,周长和费雷特直径来评估,形状通过圆度,轴向比,圆度和坚固性来评估。统计确定每个参数与临床发现之间的相关性。 FAZ尺寸参数的变异系数(CV)高于FAZ形状参数的变异系数。屈光不正和眼轴长度与面积相关因素显着相关。黄斑中央厚度(CMT)与所有参数均显着相关。尽管CMT是与FAZ的大小和形状特征显着相关的关键因素,但由于形状相关因素的CV低,形状可能是比FAZ更好地表征FAZ的因素。受其他眼部因素影响。

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