Magnetic susceptibility of a multiple sclerosis (MS) lesion increased rapidly as it changed from enhanced to nonenhanced, it attained a high susceptibility value relative to normal-appearing white matter (NAWM) during its initial few years (approximately 4 years), and it gradually dissipated back to a susceptibility value similar to that of NAWM as it aged further, which may provide new insight into the pathophysiologic features of MS lesions.
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