In Vitro Transport and Partitioning of AL-4940 Active Metabolite of Angiostatic Agent Anecortave Acetate in Ocular Tissues of the Posterior Segment

摘要

PurposeThe purpose of this study was to evaluate partitioning into and transport across posterior segment tissues (sclera, retinal pigment epithelium (RPE)–choroid) of AL-4940, the active metabolite of angiostatic cortisene anecortave acetate (AL-3789).