Improved Survival and Cure Rates With Concurrent Treatment for Multidrug-Resistant Tuberculosis–Human Immunodeficiency Virus Coinfection in South Africa

摘要

BackgroundMortality in multidrug-resistant (MDR) tuberculosis–human immunodeficiency virus (HIV) coinfection has historically been high, but most studies predated the availability of antiretroviral therapy (ART). We prospectively compared survival and treatment outcomes in MDR tuberculosis–HIV-coinfected patients on ART to those in patients with MDR tuberculosis alone.