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Nox1 transactivation of epidermal growth factor receptor promotes N-cadherin shedding and smooth muscle cell migration

机译：表皮生长因子受体的Nox1反式激活促进N-钙粘蛋白脱落和平滑肌细胞迁移

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摘要

AimsIn atherosclerosis and restenosis, vascular smooth muscle cells (SMCs) migrate into the subendothelial space and proliferate, contributing to neointimal formation. The goal of this study was to define the signalling pathway by which Nox1 NAPDH oxidase mediates SMC migration.

机译：目的在动脉粥样硬化和再狭窄中，血管平滑肌细胞（SMC）迁移到内皮下空间并增殖，从而促进新内膜的形成。这项研究的目的是确定Nox1 NAPDH氧化酶介导SMC迁移的信号通路。

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期刊名称 Cardiovascular Research
作者
Dammanahalli K. Jagadeesha; Maysam Takapoo; Botond Banfi; Ramesh C. Bhalla; Francis J. Miller Jr;
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作者单位

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年(卷),期 -1(93),3
年度 -1
页码 406–413
总页数 8
原文格式 PDF
正文语种
中图分类心血管疾病 ;
关键词
Smooth muscle cells NADPH oxidase Epidermal growth factor receptor Matrix-metalloproteinase N-cadherin;

机译：平滑肌细胞;NADPH氧化酶;表皮生长因子受体;基质金属蛋白酶;N-钙黏着蛋白;

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专利

1. Nox1 transactivation of epidermal growth factor receptor promotes N-cadherin shedding and smooth muscle cell migration [J] . JagadeeshaD.K., TakapooM., BanfiB., Cardiovascular Research . 2012 ,第3期

机译：表皮生长因子受体的Nox1反式激活促进N-钙粘蛋白脱落和平滑肌细胞迁移
2. Nox1 transactivation of epidermal growth factor receptor promotes N-cadherin shedding and smooth muscle cell migration [J] . Francis J. Miller Jr Cardiovascular Research . 2012 ,第3期

机译：表皮生长因子受体的Nox1反式激活促进N-钙粘蛋白脱落和平滑肌细胞迁移
3. Transactivation of epidermal growth factor receptor after heparin-binding epidermal growth factor-like growth factor shedding in the migration of prostate cancer cells promoted by bombesin. [J] . Madarame J, Higashiyama S, Kiyota H, The Prostate . 2003 ,第3期

机译：在肝素结合的表皮生长因子样生长因子在肝素结合促进的前列腺癌细胞迁移中脱落后，表皮生长因子受体的反式激活。
4. Liquid Scanning Transmission Electron Microscopy of Individual Quantum Dots Labeling Epidermal Growth Factor Receptors in Whole Cells [C] . M. J. Dukes, D.B. Peckys, N. de Jonge Microscopy and microanalysis.;Microscopy and microanalysis. . -1

机译：标记整个细胞中表皮生长因子受体的单个量子点的液体扫描透射电子显微镜
5. Synergistic stimulation of mitogenesis of human airway smooth muscle cells by lysophosphatidic acid and epidermal growth factor. [D] . Ediger, Tracy L. 2001

机译：溶血磷脂酸和表皮生长因子协同刺激人气道平滑肌细胞的有丝分裂。
6. Angiotensin II-Induced Migration of Vascular Smooth Muscle Cells Is Mediated by p38 Mitogen-Activated Protein Kinase-Activated c-Src Through Spleen Tyrosine Kinase and Epidermal Growth Factor Receptor Transactivation [O] . Benon E. Mugabe, Fariborz A. Yaghini, Chi Young Song, -1

机译：血管紧张素II诱导的血管平滑肌细胞迁移是通过脾酪氨酸激酶和表皮生长因子受体反式激活的p38丝裂原活化的蛋白激酶活化的c-Src介导的。
7. Nox1 transactivation of epidermal growth factor receptor promotes N-cadherin shedding and smooth muscle cell migration [O] . Dammanahalli K. Jagadeesha, Maysam Takapoo, Botond Banfi, 2011

机译：表皮生长因子受体的NOx1反式激活促进了N-cadherin脱落和平滑肌细胞迁移

Nox1 transactivation of epidermal growth factor receptor promotes N-cadherin shedding and smooth muscle cell migration

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