首页> 美国卫生研究院文献>International Journal of Clinical and Experimental Medicine >A modified porous tantalum implant technique for osteonecrosis of the femoral head: survivorship analysis and prognostic factors for radiographic progression and conversion to total hip arthroplasty
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A modified porous tantalum implant technique for osteonecrosis of the femoral head: survivorship analysis and prognostic factors for radiographic progression and conversion to total hip arthroplasty

机译:一种改良的多孔钽植入物用于股骨头坏死:影像学进展和全髋关节置换术的生存分析和预后因素

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摘要

Tantalum rod implant following core decompression is reported to be effective in early stage of osteonecrosis of the femoral head (ONFH). The purpose of this study was to assess the survivorship and prognostic factors for radiographic progression and conversion to total hip arthroplasty (THA) after treatment with a modified tantalum implant technology. 59 consecutive hips (45 patients) in whom ONFH was treated with core decompression, impaction bone grafting of 2 mm-composite bone filling material, and insertion of a porous tantalum implant. 57 hips (44 patients, mean age 43 years, range 21 to 70 years) with Steinberg Stage I-IVA ONFH were available for follow-up at a mean of 44.8 months (rang, 11 to 62 months). Outcome measures included HHS (Harris Hip Score), radiographic outcome, and survivorship analysis with reversion to THA. Radiographic progression occurred in 17 hips (17/57, 29.82%). 11 hips (11/57, 19.30%) were converted to THA. The overall survival rate was 72.49% at 60 months post-operatively. After logistic regression analysis, corticosteroid use and bone marrow edema were found to be predictors of radiographic progression. The Cox proportional-hazard model revealed that bone marrow edema was an independent prognostic factor for conversion to THA. This modified technology may make patients avoid the use of corticosteroid, especially those without bone marrow edema, and obtains encouraging survival rates and a delay in or prevention of THA.
机译:据报道,在心脏减压后使用钽棒植入物在股骨头坏死的早期有效(ONFH)。这项研究的目的是评估用改良的钽植入技术治疗后影像学进展和转换为全髋关节置换术(THA)的存活率和预后因素。对59例连续的髋关节(45例患者)进行了ONFH核心减压,2 mm复合骨填充材料的冲击骨移植,以及多孔钽植入物的治疗。接受斯坦伯格I-IVA期ONFH治疗的57例髋关节(44例患者,平均年龄43岁,范围21至70岁),平均44.8个月(11到62个月)可进行随访。结果指标包括HHS(哈里斯髋关节评分),影像学结果以及对THA的生存分析。影像学进展发生在17髋(17/57,29.82%)。 11髋(11/57,19.30%)被转换为THA。术后60个月的总生存率为72.49%。经逻辑回归分析后,发现使用皮质类固醇激素和骨髓水肿是影像学进展的预测指标。 Cox比例风险模型显示,骨髓水肿是转化为THA的独立预后因素。这种改良的技术可以使患者避免使用皮质类固醇,尤其是那些没有骨髓水肿的患者,并获得令人鼓舞的生存率以及THA的延迟或预防。

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