3-(2-Amino­ethyl)-2-(4-chloro­anilino)­quinazolin-4(3H)-one methanol 0.75-solvate

摘要

In the asymmetric unit of the title compound, C16H15ClN4O·0.75CH3OH, there are two independent quinazolin-4(3H)-one mol­ecules and one and a half methanol mol­ecules. One of the methanol mol­ecules is disordered over two positions with equal occupancies. The dihedral angles between the quinazoline ring system and the chloro­benzene ring in the two quinazolin-4(3H)-one mol­ecules are essentially the same, at 39.83 (1) and 39.84 (1)°. Intra­molecular N—H⋯N and O—H⋯O, and inter­molecular N—H⋯O and N—H⋯N hydrogen bonds are observed. In addition, π–π stacking inter­actions, with centroid-to-centroid distances of 3.654 (1), 3.766 (1) and 3.767 (1) Å, and weak C—H⋯π inter­actions, are observed.