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Effects of a novel ascorbate-based protocol on infarct size and ventricle function in acute myocardial infarction patients undergoing percutaneous coronary angioplasty

机译：一种基于抗坏血酸的新方案对经皮冠状动脉成形术的急性心肌梗死患者梗死面积和心室功能的影响

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IntroductionThis study was designed to test the hypothesis that high-dose ascorbate prior to reperfusion followed by low chronic oral doses ameliorate myocardial reperfusion injury (MRI) in acute myocardial infarction patients subjected to primary percutaneous coronary angioplasty (PCA).

机译：简介本研究旨在检验以下假设，即在接受原发性经皮冠状动脉成形术（PCA）的急性心肌梗死患者中，高剂量抗坏血酸再灌注后再低剂量的慢性口服剂量可改善心肌再灌注损伤（MRI）。

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期刊名称 Archives of Medical Science : AMS
作者
Cristóbal Ramos; Roberto Brito; Jaime González-Montero; Nicolás Valls; Juan G. Gormaz; Juan C. Prieto; Rubén Aguayo; Ángel Puentes; Viviana Noriega; Gonzalo Pereira; Tamara Palavecino; Ramón Rodrigo;
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作者单位

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年(卷),期 2017(13),3
年度 2017
页码 558–567
总页数 10
原文格式 PDF
正文语种
中图分类基础医学;
关键词
ascorbate myocardial reperfusion injury oxidative stress;

机译：抗坏血酸;心肌再灌注损伤;氧化应激;

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专利

1. Effects of nicorandil on myocardial infarct size in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: study design and protocol for the randomized controlled trial [J] . Xiao-Si JIANG, Zong-Zhuang LI, Yong-Jun LI, 老年心脏病学杂志（英文版） . 2020,第008期

机译：尼可地尔对ST段抬高型心肌梗死初次经皮冠状动脉介入治疗患者心肌梗死面积的影响：随机对照试验的研究设计和方案
2. Usefulness of Early Treatment With Melatonin to Reduce Infarct Size in Patients With ST-Segment Elevation Myocardial Infarction Receiving Percutaneous Coronary Intervention (From the Melatonin Adjunct in the Acute Myocardial Infarction Treated With Angioplasty Trial) [J] . Dominguez-Rodriguez Alberto, Abreu-Gonzalez Pedro, de la Torre-Hernandez Jose M., The American Journal of Cardiology . 2017,第4期

机译：用褪黑素早期治疗的有用性降低患有经皮冠状动脉介入的ST段抬高心肌梗死患者的梗塞大小（从血管成形术试验治疗的急性心肌梗死中的褪黑激素辅助）
3. Letter by Khan and Boyle Regarding Article, "Early Use of N-Acetylcysteine (NAC) With Nitrate Therapy in Patients Undergoing Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction Reduces Myocardial Infarct Size (The NACIAM Trial [N-Acetylcysteine in Acute Myocardial Infarction])" [J] . Khan Arshad A., Boyle Andrew J. Circulation: An Official Journal of the American Heart Association . 2018,第13期

机译：Khan和Boyle关于文章的信，“早期使用N-乙酰半胱氨酸（NAC）与硝酸盐治疗患者进行初前经皮冠状动脉介入的ST段抬高心肌梗死减少了心肌梗塞大小（Naciam试验[N-乙酰半胱氨酸在急性心肌中梗塞]）“
4. In-hospital Outcome in Octogenarians with Acute Myocardial Infarction Undergoing Primary Coronary Angioplasty [C] . Kenji Ando, Soga Yoshimitsu, Kei Nishiyama, International Congress on Coronary Artery Disease . 2003

机译：在八分类药物中的急性心肌梗死接受初级冠状动脉血管成形术治疗
5. Meta-analysis: The impact of thrombectomy during PCI (percutaneous coronary intervention) on mortality, re-infarction and target vessel revascularization among patients with ST elevation myocardial infarction compared with standard PCI. [D] . Martar, Martar. 2016

机译：荟萃分析：与标准PCI相比，ST抬高型心肌梗死患者在PCI（经皮冠状动脉介入治疗）期间进行血栓切除术对死亡率，再梗塞和靶血管血运重建的影响。
6. Effects of nicorandil on myocardial infarct size in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: study design and protocol for the randomized controlled trial [O] . Xiao-Si JIANG, Li-Chao TIAN, Zi-Chao JIANG, 2020

机译：Nicorandil对初级经皮冠状动脉干预患者心肌梗死大小的影响：随机对照试验的研究设计与议定书
7. Effect of early metoprolol on infarct size in ST-segment elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: The effect of metoprolol in cardioprotection during an acute myocardial infarction (METOCARD-CNIC) trial BorjaIbanezCarlosMacayaVicenteSanchez-BruneteGonzaloPizzaroLeticiaFernandez-FrieraValentinFusterEffect of early metoprolol on infarct size in ST-segment elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: The effect of metoprolol in cardioprotection during an acute myocardial infarction (METOCARD-CNIC) trialCirculation128201314951503originally published online September 3, 2013 [O] . Khanal Suraj, Vadivelu R. 2014

机译：早期美托洛尔对接受初次经皮冠状动脉介入治疗的ST段抬高型心肌梗死患者的梗死面积的影响：美托洛尔在急性心肌梗死（METOCARD-CNIC）试验中的心脏保护作用中的作用ST段抬高型心肌梗死患者接受初次经皮冠状动脉介入治疗：美托洛尔在急性心肌梗塞（METOCARD-CNIC）试验期间对心脏保护的作用循环128201314951503最初于2013年9月3日在线发布

Effects of a novel ascorbate-based protocol on infarct size and ventricle function in acute myocardial infarction patients undergoing percutaneous coronary angioplasty

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