Proteomic analysis on N N′-dinitrosopiperazine-mediated metastasis of nasopharyngeal carcinoma 6-10B cells

摘要

BackgroundNasopharyngeal carcinoma (NPC) has a high metastatic feature. N,N^′-Dinitrosopiperazine (DNP) is involved in NPC metastasis, but its mechanism is not clear. The aim of this study is to reveal the pathogenesis of DNP-involved metastasis. 6-10B cells with low metastasis are from NPC cell line SUNE-1, were used to investigate the mechanism of DNP-mediated NPC metastasis.