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DensityMap: a genome viewer for illustrating the densities of features

机译:DensityMap:用于说明特征密度的基因组查看器

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摘要

BackgroundSeveral tools are available for visualizing genomic data. Some, such as Gbrowse and Jbrowse, are very efficient for small genomic regions, but they are not suitable for entire genomes. Others, like Phenogram and CViT, can be used to visualise whole genomes, but are not designed to display very dense genomic features (eg: interspersed repeats). We have therefore developed DensityMap, a lightweight Perl program that can display the densities of several features (genes, ncRNA, cpg, etc.) along chromosomes on the scale of the whole genome. A critical advantage of DensityMap is that it uses GFF annotation files directly to compute the densities of features without needing additional information from the user. The resulting picture is readily configurable, and the colour scales used can be customized for a best fit to the data plotted.
机译:背景有几种工具可用于可视化基因组数据。有些,例如Gbrowse和Jbrowse,对于小的基因组区域非常有效,但是它们并不适合整个基因组。诸如Phenogram和CViT的其他序列可用于可视化整个基因组,但并非旨在显示非常密集的基因组特征(例如:散布的重复序列)。因此,我们开发了DensityMap,这是一个轻量级的Perl程序,可以在整个基因组范围内沿染色体显示几个特征(基因,ncRNA,cpg等)的密度。 DensityMap的一个关键优势是它直接使用GFF批注文件来计算要素的密度,而无需用户提供其他信息。生成的图片易于配置,可以定制所使用的色标,以使其最适合所绘制的数据。

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