SlowFaster a user-friendly program for slow-fast analysis and its application on phylogeny of Blastocystis

摘要

BackgroundSlow-fast analysis is a simple and effective method to reduce the influence of substitution saturation, one of the causes of phylogenetic noise and long branch attraction (LBA) artifacts. In several steps of increasing stringency, the slow-fast analysis omits the fastest substituting alignment positions from the analysed dataset and thus increases its signaloise ratio.