Detection of Helicobacter pylori and its virulence genes (cagA dupA and vacA) among patients with gastroduodenal diseases in Chris Hani Baragwanath Academic Hospital South Africa

摘要

BackgroundThe global prevalence of H. pylori approaches 50%, with prevalence rates between 20 and 40% in developed countries and up to 90% in Africa and other developing nations of the world. Development of H. pylori-associated diseases is determined by a number of virulence factors. This study aimed at determining the prevalence of H. pylori infections and virulence genes (cagA, dupA, and vacA); the relationship between virulence factors and gastroduodenal diseases among patients.