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Impact of gene variants on sex-specific regulation of human Scavenger receptor class B type 1 (SR-BI) expression in liver and association with lipid levels in a population-based study

机译：在一项基于人群的研究中基因变异对人类清道夫受体B类1型（SR-BI）表达在肝脏中的性别特异性调节及其与脂质水平的关系的影响

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BackgroundSeveral studies have noted that genetic variants of SCARB1, a lipoprotein receptor involved in reverse cholesterol transport, are associated with serum lipid levels in a sex-dependent fashion. However, the mechanism underlying this gene by sex interaction has not been explored.

机译：背景多项研究表明，SCARB1（参与反向胆固醇转运的脂蛋白受体）的遗传变异与性别相关的血清脂质水平相关。但是，尚未探索该基因通过性别相互作用的机制。

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期刊名称 BMC Medical Genetics
作者
Ornit Chiba-Falek; Marshall Nichols; Sunil Suchindran; John Guyton; Geoffrey S Ginsburg; Elizabeth Barrett-Connor; Jeanette J McCarthy;
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年(卷),期 2010(11),-1
年度 2010
页码 9
总页数 12
原文格式 PDF
正文语种
中图分类遗传学;
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专利

1. Impact of gene variants on sex-specific regulation of human Scavenger receptor class B type 1 (SR-BI) expression in liver and association with lipid levels in a population-based study [J] . Ornit Chiba-Falek, Marshall Nichols, Sunil Suchindran, BMC Medical Genetics . 2010,第1期

机译：一项基于人群的研究中，基因变异对人类清道夫受体B类1型（SR-BI）表达在肝脏中的性别特异性调节及其与脂质水平的关系
2. Restoration of high-density lipoprotein levels by cholesteryl ester transfer protein expression in scavenger receptor class B type I (SR-BI) knockout mice does not normalize pathologies associated with SR-BI deficiency. [J] . Hildebrand RB, Lammers B, Meurs I, Arteriosclerosis, thrombosis, and vascular biology . 2010,第7期

机译：通过清除剂受体B类I型（SR-BI）敲除小鼠中的胆固醇酯转移蛋白表达恢复高密度脂蛋白水平不能使与SR-BI缺乏相关的病理正常化。
3. Down-regulation of intestinal scavenger receptor class B, type I (SR-BI) expression in rodents under conditions of deficient bile delivery to the intestine. [J] . Voshol PJ, Schwarz M, Rigotti A, The Biochemical Journal . 2001,第Pta2期

机译：在胆汁输送到肠道的条件不足的情况下，啮齿动物肠道清除剂受体B类I型（SR-BI）表达下调。
4. Function and regulation of hepatic scavenger receptor class B type I (SR-BI) [C] . International Symposium on Atherosclerosis . 2004

机译：肝清除剂受体B类的功能和调节I（SR-BI）
5. Genetic regulation of sex-specific gene expression in mouse liver. [D] . Zhao, Ni. 2009

机译：小鼠肝脏中性别特异性基因表达的遗传调控。
6. Impact of Genetic Variants in Human Scavenger Receptor Class B Type I (SCARB1) on Plasma Lipid Traits [O] . Vipavee Niemsiri, Xingbin Wang, Dilek Pirim, -1

机译：人类清除剂受体B类I（SCARB1）遗传变异对血浆脂质特性的影响
7. Impact of gene variants on sex-specific regulation of human Scavenger receptor class B type 1 (SR-BI) expression in liver and association with lipid levels in a population-based study [O] . Ornit Chiba-Falek, Marshall Nichols, Sunil Suchindran, 2010

机译：在一项基于人群的研究中，基因变异对人类清道夫受体B类1型（SR-BI）表达在肝脏中的性别特异性调节及其与脂质水平的关系的影响

Impact of gene variants on sex-specific regulation of human Scavenger receptor class B type 1 (SR-BI) expression in liver and association with lipid levels in a population-based study

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