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MAD2 Expression in Ovarian Carcinoma: Different Expression Patterns and Levels among Various Types of Ovarian Carcinoma and Its Prognostic Significance in High-Grade Serous Carcinoma

机译：MAD2在卵巢癌中的表达：各种类型的卵巢癌之间的不同表达模式和水平及其在高度浆液性癌中的预后意义

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BackgroundMitotic arrest deficiency protein 2 (MAD2) is a key component of spindle assembly checkpoint function, which mediates cell apoptosis through microtubule kinetics. Aberrant expression of MAD2 is believed to be associated with the development of chromosome instability. MAD2 also has a signihicant role in cellular drug resistance to taxane chemotherapeutic agents.

机译：背景有丝分裂阻滞缺乏蛋白2（MAD2）是纺锤体装配检查点功能的关键组成部分，其通过微管动力学介导细胞凋亡。据信MAD2的异常表达与染色体不稳定性的发展有关。 MAD2在细胞对紫杉烷化学治疗剂的耐药性中也具有重要作用。

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期刊名称 Journal of Pathology and Translational Medicine
作者
Po Eun Park; Ji Yun Jeong; Sun Zoo Kim; Ji Young Park;
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作者单位

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年(卷),期 2013(47),5
年度 2013
页码 418–425
总页数 8
原文格式 PDF
正文语种
中图分类病理学;
关键词
MAD2L1 protein human; Ovarian neoplasms; Cell cycle checkpoints; Taxane;

机译：MAD2L1蛋白;人类;卵巢肿瘤;细胞周期检查点;紫杉烷;

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1. PD-L1 Expression and CD8(+) Tumor-infiltrating Lymphocytes in Different Types of Tubo-ovarian Carcinoma and Their Prognostic Value in High-grade Serous Carcinoma [J] . American Journal of Surgical Pathology . 2020,第8期

机译：PD-L1表达和CD8（+）肿瘤浸润淋巴细胞在不同类型的卵巢癌癌及其高级浆液癌中的预后价值
2. Prognostic significance of Ki-67 levels and hormone receptor expression in low-grade serous ovarian carcinoma: an investigation of the Tumor Bank Ovarian Cancer Network [J] . Sehouli Jalid, Braicu Elena Ioana, Richter Rolf, Human Pathology . 2019,第期

机译：低级浆液癌中KI-67水平和激素受体表达的预后意义：肿瘤储备卵巢癌网络的研究
3. Profile of differentially expressed miRNAs in high-grade serous carcinoma and clear cell ovarian carcinoma, and the expression of miR-510 in ovarian carcinoma [J] . Zhang Xinchen, Guo Gordon, Wang Guang, Molecular medicine reports . 2015,第6期

机译：高度浆液性癌和透明细胞卵巢癌中差异表达的miRNA的概况以及miR-510在卵巢癌中的表达
4. Global proteomic analysis of ovarian high-grade serous carcinomas using SWATH-MS for targeted verification of proteome changes associated with genomic alterations [C] . Stefani N. Thomas, Jing Chen, Paul Aiyetan, ASMS Conference on Mass Spectrometry and Allied Topics . 2015

机译：卵巢高级浆液癌的全局蛋白质组学分析使用SWATH-MS进行靶向验证与基因组改变相关的蛋白质组变化
5. Inhibitory Functions of SUSD2 in the Progression of High-Grade Serous Ovarian Carcinoma. [D] . Sheets, Jordan N. 2017

机译：SUSD2在高级浆液性卵巢癌进展中的抑制作用。
6. Characterization of desmoglein 2 expression in ovarian serous tumors and its prognostic significance in high-grade serous carcinoma [O] . Ling Chen, Xinxin Liu, Jin Zhang, 2018

机译：卵巢浆液肿瘤中脱胶2表达的表征及其高级浆液癌的预后意义
7. MAD2 Expression in Ovarian Carcinoma: Different Expression Patterns and Levels among Various Types of Ovarian Carcinoma and Its Prognostic Significance in High-Grade Serous Carcinoma [O] . Po Eun Park, Ji Yun Jeong, Sun Zoo Kim, 2013

机译：卵巢癌中的Mad2表达：各种类型的卵巢癌中的不同表达模式和水平及其在高级浆液癌中的预后意义

MAD2 Expression in Ovarian Carcinoma: Different Expression Patterns and Levels among Various Types of Ovarian Carcinoma and Its Prognostic Significance in High-Grade Serous Carcinoma

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