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The clinical meaningfulness of ADAS-Cog changes in Alzheimers disease patients treated with donepezil in an open-label trial

机译：公开试验中多奈哌齐治疗阿尔茨海默氏病患者ADAS-Cog变化的临床意义

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BackgroundIn 6-month anti-dementia drug trials, a 4-point change in the Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog) is held to be clinically important. We examined how this change compared with measures of clinical meaningfulness.

机译：背景在为期6个月的抗痴呆药物试验中，阿尔茨海默氏病疾病评估量表-认知亚量表（ADAS-Cog）的4分变化被认为具有重要的临床意义。我们检查了这种变化与临床意义测量之间的比较。

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期刊名称 BMC Neurology
作者
Kenneth Rockwood; Sherri Fay; Mary Gorman; Daniel Carver; Janice E Graham;
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年(卷),期 2007(7),-1
年度 2007
页码 26
总页数 8
原文格式 PDF
正文语种
中图分类神经病学;
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专利

1. The clinical meaningfulness of ADAS-Cog changes in Alzheimer's disease patients treated with donepezil in an open-label trial [J] . Kenneth Rockwood, Sherri Fay, Mary Gorman, BMC Neurology . 2007,第1期

机译：公开试验中多奈哌齐治疗阿尔茨海默氏病患者ADAS-Cog变化的临床意义
2. The ADAS-cog and clinically meaningful change in the VISTA clinical trial of galantamine for Alzheimer's disease. [J] . Rockwood K, Fay S, Gorman M International journal of geriatric psychiatry . 2010,第2期

机译：加兰他敏治疗阿尔茨海默氏病的VISTA临床试验中的ADAS-cog和具有临床意义的变化。
3. Safety and tolerability of donepezil 23?mg with or without intermediate dose titration in patients with Alzheimer’s disease taking donepezil 10?mg: a multicenter, randomized, open-label, parallel-design, three-arm, prospective trial [J] . Yun Jeong Hong, Hyun Jeong Han, Young Chul Youn, Alzheimer s Research & Therapy . 2019,第1期

机译：服用多奈哌齐10毫克的阿尔茨海默氏病患者，无论是否进行中等剂量滴定，多奈哌齐23毫克的安全性和耐受性：一项多中心，随机，开放标签，平行设计，三臂，前瞻性试验
4. Cerebral perfusion patterns associated with the clinical response to donepezil therapy in Alzheimer's disease patients [C] . Haruo Hanyu, Soichiro Shimizu, Kentaro Hirao, International Symposium on Functional and Molecular Imaging of Stroke and Dementia . 2006

机译：与临床反应相关的脑灌注模式在阿尔茨海默病患者患者中的临床反应相关
5. Efficacy and safety of novel collagen conduits filled with collagen filaments to treat patients with peripheral nerve injury: A multicenter, controlled, open-label clinical trial [D] . Saeki Masaomi, 佐伯将臣 2019

机译：充满胶原细丝的新型胶原蛋白导管治疗周围神经损伤患者的疗效和安全性：一项多中心，对照，开放标签的临床试验
6. Safety and tolerability of donepezil 23 mg with or without intermediate dose titration in patients with Alzheimer’s disease taking donepezil 10 mg: a multicenter randomized open-label parallel-design three-arm prospective trial [O] . Yun Jeong Hong, Hyun Jeong Han, Young Chul Youn, 2019

机译：服用多奈哌齐10毫克的阿尔茨海默氏病患者无论是否进行中等剂量滴定多奈哌齐23毫克的安全性和耐受性：多中心随机开放标签平行设计三臂前瞻性试验
7. The clinical meaningfulness of ADAS-Cog changes in Alzheimer's disease patients treated with donepezil in an open-label trial [O] . 2007

机译：公开试验中多奈哌齐治疗阿尔茨海默氏病患者ADAS-Cog改变的临床意义

The clinical meaningfulness of ADAS-Cog changes in Alzheimers disease patients treated with donepezil in an open-label trial

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