A randomized double-blind crossover placebo-controlled clinical trial to assess effects of the single ingestion of a tablet containing lactoferrin lactoperoxidase and glucose oxidase on oral malodor

摘要

BackgroundThe main components of oral malodor have been identified as volatile sulfur compounds (VSCs) including hydrogen sulfide (H2S) and methyl mercaptan (CH3SH). VSCs also play an important role in the progression of periodontal disease. The aim of the present study was to assess the effects of the single ingestion of a tablet containing 20 mg of lactoferrin, 2.6 mg of lactoperoxidase, and 2.6 mg of glucose oxidase on VSCs in the mouth.