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Unusual presentation of more common disease/injury: Solitary fibrous tumour of the lower leg: an uncommon site with atypical histopathological features

机译:较常见的疾病/损伤的异常表现:下肢孤立性纤维性肿瘤:具有非典型组织病理学特征的罕见部位

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摘要

A 40-year-old man of low socioeconomic status presented with a slowly growing painless mass for 1 year at the antero-medial aspect of the right leg. On local examination, the overlying skin was normal and the mass was soft to firm in consistency, non-tender and freely mobile with no fixity to underlying structures. MRI revealed a lobulated mass with central areas of necrosis and no involvement of underlying muscles and neurovascular bundles suggesting a benign soft tissue tumour. The tumour was totally excised and submitted for histopathological examination, which, along with immunopositivity for CD34, CD99 and focally for Bcl2, led to a confirmatory diagnosis of solitary fibrous tumour with atypical histopathological features of increased mitosis and necrosis. After 4 months of follow-up, the patient was disease free without any recurrence or metastasis.
机译:一名40岁的社会经济地位低下的男子,右腿前内侧表现为缓慢增长的无痛肿块,持续了1年。经局部检查,上覆皮肤正常,肿块柔软,结实,不嫩,可自由活动,对下层结构无固定性。 MRI显示小叶状肿块,中央有坏死区域,无累及下层肌肉和神经血管束,提示软组织良性肿瘤。将肿瘤完全切除并进行组织病理学检查,再加上对CD34,CD99和Bcl2的免疫阳性,可以确诊诊断为孤立的纤维性肿瘤,具有非典型的组织病理学特征,即有丝分裂和坏死增加。随访4个月后,患者无疾病,无任何复发或转移。

著录项

  • 期刊名称 BMJ Case Reports
  • 作者

    Rana K Sherwani; Amit Kumar;

  • 作者单位
  • 年(卷),期 2010(2010),-1
  • 年度 2010
  • 页码 bcr0520102970
  • 总页数 4
  • 原文格式 PDF
  • 正文语种
  • 中图分类
  • 关键词

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