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Impact of CTLA-4 blockade in conjunction with metronomic chemotherapy on preclinical breast cancer growth

机译：CTLA-4阻断结合节律化疗对临床前乳腺癌生长的影响

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摘要

Background: Although there are reports that metronomic cyclophosphamide (CTX) can be immune stimulating, the impact of its combination with anti-CTLA-4 immunotherapy for the treatment of cancer remains to be evaluated.

机译：背景：尽管有报道说节律性环磷酰胺（CTX）可以免疫刺激，但将其与抗CTLA-4免疫疗法联合使用对癌症的治疗效果尚待评估。

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期刊名称 British Journal of Cancer
作者
Karla Parra; Paloma Valenzuela; Natzidielly Lerma; Alejandra Gallegos; Luis C Reza; Georgialina Rodriguez; Urban Emmenegger; Teresa Di Desidero; Guido Bocci; Mitchell S Felder; Marian Manciu; Robert A Kirken; Giulio Francia;
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年(卷),期 2017(116),3
年度 2017
页码 324–334
总页数 11
原文格式 PDF
正文语种
中图分类肿瘤学;
关键词
immunotherapy metronomic chemotherapy orthotopic CTLA-4 cyclophosphamide gemcitabine;

机译：免疫疗法;节律化疗;原位;CTLA-4;环磷酰胺;吉西他滨;

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专利

1. Impact of CTLA-4 blockade in conjunction with metronomic chemotherapy on preclinical breast cancer growth [J] . KarlaParra, PalomaValenzuela, NatzidiellyLerma, British Journal of Cancer . 2017,第3期

机译：CTLA-4阻断结合节律化疗对临床前乳腺癌生长的影响
2. Phase I/II trial of metronomic chemotherapy with daily dalteparin and cyclophosphamide, twice-weekly methotrexate, and daily prednisone as therapy for metastatic breast cancer using vascular endothelial growth factor and soluble vascular endothelial growth factor receptor levels as markers of response. [J] . Wong NS, Buckman RA, Clemons Journal of Clinical Oncology . 2010,第5期

机译：使用每日达特肝素和环磷酰胺，每周两次甲氨蝶呤和每日泼尼松作为转移性乳腺癌治疗的节律化疗的I / II期临床试验，使用血管内皮生长因子和可溶性血管内皮生长因子受体水平作为反应指标。
3. Combination Immunotherapy of MUC1 mRNA Nano-vaccine and CTLA-4 Blockade Effectively Inhibits Growth of Triple Negative Breast Cancer [J] . Lina Liu, Yuhua Wang, Lei Miao, Molecular therapy: the journal of the American Society of Gene Therapy . 2018,第1期

机译：Muc1 mRNA纳米疫苗和CTLA-4封闭的组合免疫疗法有效抑制了三重阴性乳腺癌的生长
4. PERFECTO: Prediction of Extended Response and Growth Functions for Estimating Chemotherapy Outcomes in Breast Cancer [C] . Daria Kurz, Cristian Axenie IEEE International Conference on Bioinformatics and Biomedicine . 2020

机译：Perfecto：预测对乳腺癌化疗结果的扩展反应和生长功能
5. Predicting chemotherapy resistance in breast cancer patients using radiofluorinated analogues of chemotherapy agents in conjunction with positron emission tomography. [D] . Kesner, Amanda Lovell. 2003

机译：结合使用化疗剂的放射性氟化类似物和正电子发射断层扫描术，可以预测乳腺癌患者的化疗耐药性。
6. Combination Immunotherapy of MUC1 mRNA Nano-vaccine and CTLA-4 Blockade Effectively Inhibits Growth of Triple Negative Breast Cancer [O] . Lina Liu, Yuhua Wang, Lei Miao, 2018

机译：MUC1 mRNA纳米疫苗和CTLA-4阻断的联合免疫疗法有效抑制三阴性乳腺癌的生长。
7. Impact of CTLA-4 blockade in conjunction with metronomic chemotherapy on preclinical breast cancer growth [O] . Parra, Karla, Valenzuela, Paloma, Lerma, Natzidielly, 2017

机译：CTLA-4阻断结合节律化疗对临床前乳腺癌生长的影响

Impact of CTLA-4 blockade in conjunction with metronomic chemotherapy on preclinical breast cancer growth

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