Time course of the increase in 4β-hydroxycholesterol concentration during carbamazepine treatment of paediatric patients with epilepsy

机译：卡马西平治疗小儿癫痫患者中4β-羟基胆固醇浓度增加的时程

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摘要

AIMSTo investigate the time course of the increase in 4β-hydroxycholesterol and carbamazepine plasma concentrations during treatment of paediatric patients with epilepsy.

机译：目的探讨治疗小儿癫痫患者中4β-羟基胆固醇和卡马西平血药浓度升高的时程。

著录项

期刊名称 British Journal of Clinical Pharmacology
作者
Katarina Wide; Hanna Larsson; Leif Bertilsson; Ulf Diczfalusy;
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作者单位

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年(卷),期 2008(65),5
年度 2008
页码 708–715
总页数 8
原文格式 PDF
正文语种
中图分类药学;
关键词
4β-hydroxycholesterol carbamazepine CYP3A4 CYP3A5 epilepsy;

机译：4β-羟基胆固醇;卡马西平;CYP3A4;CYP3A5;癫痫;

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专利

1. Time course of the increase in 4beta-hydroxycholesterol concentration during carbamazepine treatment of paediatric patients with epilepsy. [J] . Wide K, Larsson H, Bertilsson L, British Journal of Clinical Pharmacology . 2008,第5期

机译：卡马西平治疗小儿癫痫患者中4β-羟基胆固醇浓度增加的时间过程。
2. Time course of the increase in 4-hydroxycholesterol concentration during carbamazepine treatment of paediatric patients with epilepsy [J] . Katarina Wide, Hanna Larsson, Leif Bertilsson, British journal of clinical pharmacology . 2008,第5期

机译：卡马西平治疗小儿癫痫患者中4-羟基胆固醇浓度增加的时程
3. Chronic treatment of human astrocytoma cells with lithium, carbamazepine or valproic acid decreases inositol uptake at high inositol concentrations but increases it at low inositol concentrations. [J] . Wolfson M, Bersudsky Y, Zinger E, Brain research . 2000,第1期

机译：用锂，卡马西平或丙戊酸对人星形细胞瘤细胞进行慢性处理，可在高肌醇浓度下降低肌醇摄取，但在低肌醇浓度下可增加摄取。
4. Area under the concentrations versus time curve (AUC) based busulfan exposure monitoring in paediatric patients [C] . Tesfaye H., Klapkova E., Prusa R. European Association for Clinical Pharmacology and Therapeutics . 2009

机译：浓度下的面积与时间曲线（AUC）基于小儿患者的Busulfan暴露监测
5. The Increased Risk of Mortality in Elderly Patients with Epilepsy and Dementias. [D] . Andrade, Rogger Americo. 2007

机译：老年癫痫和痴呆患者的死亡风险增加。
6. Population Pharmacokinetics of Unbound and Total Drug Concentrations Following Intravenously Administered Carbamazepine in Elderly and Younger Adult Patients With Epilepsy [O] . Ghada F. Ahmed, Richard C. Brundage, Susan E. Marino, -1

机译：在老年人和患者癫痫患者中静脉内施用的尸毒血管术后未绑定和总药物浓度的人口药代动力学
7. Time course of the increase in 4β-hydroxycholesterol concentration during carbamazepine treatment of paediatric patients with epilepsy [O] . Wide, Katarina, Larsson, Hanna, Bertilsson, Leif, 2008

机译：卡马西平治疗小儿癫痫患者中4β-羟基胆固醇浓度增加的时程

Time course of the increase in 4β-hydroxycholesterol concentration during carbamazepine treatment of paediatric patients with epilepsy

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