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Systematically profiling the expression of eIF3 subunits in glioma reveals the expression of eIF3i has prognostic value in IDH-mutant lower grade glioma

机译：系统地分析神经胶质瘤中eIF3亚基的表达揭示eIF3i的表达对IDH突变的低级神经胶质瘤具有预后价值

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摘要

BackgroundAbnormal expression of the eukaryotic initiation factor 3 (eIF3) subunits plays critical roles in tumorigenesis and progression, and also has potential prognostic value in cancers. However, the expression and clinical implications of eIF3 subunits in glioma remain unknown.

机译：背景真核生物起始因子3（eIF3）亚基的异常表达在肿瘤发生和发展中起关键作用，并且在癌症中也具有潜在的预后价值。然而，eIF3亚基在神经胶质瘤中的表达及其临床意义仍然未知。

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期刊名称 Cancer Cell International
作者
Rui-Chao Chai; Ning Wang; Yu-Zhou Chang; Ke-Nan Zhang; Jing-Jun Li; Jun-Jie Niu; Fan Wu; Yu-Qing Liu; Yong-Zhi Wang;
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作者单位

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年(卷),期 2019(19),-1
年度 2019
页码 155
总页数 13
原文格式 PDF
正文语种
中图分类肿瘤学;
关键词
eIF3 Glioma 1p/19q codeletion Prognosis Biomarker;

机译：eIF3;神经胶质瘤;1p / 19q编码;预后;生物标志物;

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专利

1. 水稻eIF3大亚基(eIF3a)编码基因的克隆及其表达模式分析 [J] . 李竑, 沈思师, 许智宏, 分子细胞生物学报（英文版） . 2003,第001期
2. c-Met Expression Is a Useful Marker for Prognosis Prediction in IDH-Mutant Lower-Grade Gliomas and IDH-Wildtype Glioblastomas [J] . Ohba Shigeo, Yamada Yasuhiro, Murayama Kazuhiro, World neurosurgery . 2019,第期

机译：C-Met表达是IDH-突变体较低级Gliomas和IDH-Wildtype Glioblastomas预后预测的有用标志物
3. ADAM9 Expression Is Associate with Glioma Tumor Grade and Histological Type, and Acts as a Prognostic Factor in Lower-Grade Gliomas [J] . Xing Fan, Yongheng Wang, Chuanbao Zhang, International Journal of Molecular Sciences . 2016,第9期

机译：ADAM9表达与神经胶质瘤的肿瘤分级和组织学类型有关，并作为低级胶质瘤的预后因素
4. ADAM9 Expression Is Associate with Glioma Tumor Grade and Histological Type, and Acts as a Prognostic Factor in Lower-Grade Gliomas [J] . Xing Fan, Yongheng Wang, Chuanbao Zhang, International Journal of Molecular Sciences . 2016,第9期

机译：ADAM9表达与神经胶质瘤的肿瘤分级和组织学类型有关，并作为低级胶质瘤的预后因素
5. Gene Expression Profiling of Human Gliomas [C] . ME. Hegi, S. Godard, G. Getz, European Congress of Neurosurgery . 2003

机译：人胶质瘤的基因表达谱
6. Gene expression profiling of chemoresistance in human malignant gliomas. [D] . Rhiew, Richard B. 2004

机译：人类恶性神经胶质瘤中化学抗性的基因表达谱。
7. ADAM9 Expression Is Associate with Glioma Tumor Grade and Histological Type and Acts as a Prognostic Factor in Lower-Grade Gliomas [O] . Xing Fan, Yongheng Wang, Chuanbao Zhang, 2016

机译：ADAM9表达与神经胶质瘤的肿瘤等级和组织学类型有关并作为低级胶质瘤的预后因素
8. Identification of IDH-mutant gliomas by a prognostic signature according to gene expression profiling [O] . Qiangwei Wang, Zhiliang Wang, Guanzhang Li, 2018

机译：根据基因表达分析，通过预后签名鉴定IDH突变胶质瘤

Systematically profiling the expression of eIF3 subunits in glioma reveals the expression of eIF3i has prognostic value in IDH-mutant lower grade glioma

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