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Combined Kidney-Liver Heart-Liver and Kidney-Pancreas Transplantations from a Single Deceased Donor

机译:单个死者的肾脏-肝脏心脏-肝脏和肾脏-胰腺联合移植

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摘要

Splitting the liver for two adults to increase the donor pool is still a debated issue, especially for combined organ transplantation. We described a case of liver-splitting procedure for two adults, which was successful even in the presence of combined organ transplantation. Three adult combined organ transplantations from one deceased donor were performed, with, use of split liver grafts in two patients: a combined heart-right split liver, a left kidney-left split liver, and a right kidney-pancreas transplantation. Despite a not perfect match between the graft type and recipient, the prevention of small-for-size syndrome by ligature of the splenic artery, and/or hemiportocaval shunt in the patient receiving the left split liver, and the maximal reduction of ischemia time were the main factors contributing to the success of the procedure. This is the first report of combined heart and split liver in two adults which may suggest new strategies for organ transplantations.
机译:拆分两个成年人的肝脏以增加供体库仍然是一个有争议的问题,尤其是对于器官联合移植。我们描述了一个有两名成年人进行肝分裂手术的案例,即使在存在联合器官移植的情况下,该案例也是成功的。进行了三例来自一名死者供体的成人联合器官移植,并在两名患者中使用了肝分割移植:心右肝分割联合,左肾左肝分割联合和右胰胰腺移植。尽管移植物类型和受体之间的匹配不完全,但在接受左肝分割的患者中,通过脾脏动脉的结扎和/或半门静脉分流术可以预防小尺寸综合征,并且最大程度地缩短了缺血时间影响手术成功的主要因素。这是两个成年人合并心脏和肝脏分裂的首次报道,这可能为器官移植提出了新的策略。

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