Expression analysis of beta-secretase 1 (BACE1) enzyme in peripheral blood of patients with Alzheimers disease

摘要

Background:Recent evidence has indicated that beta-secretase 1 (BACE1) is involved in the production of amyloid beta (Aβ) in patients affected with Alzheimer’s disease (AD). Therefore; the purpose of this study was to measure mRNA and plasma levels of BACE1 in AD patients, as an early diagnosis biomarker for such individuals.