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Modifying Clopidogrel Maintenance Doses According to Vasodilator‐Stimulated Phosphoprotein Phosphorylation Index Improves Clinical Outcome in Patients With Clopidogrel Resistance

机译：根据血管扩张剂刺激的磷酸蛋白磷酸化指数修改氯吡格雷维持剂量可改善氯吡格雷抵抗性患者的临床疗效

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Background:Despite dual antiplatelet therapy, the rate of major adverse cardiovascular events (MACE) after percutaneous coronary intervention (PCI) remains high. Ex vivo tests of clopidogrel resistance can predict MACE after PCI. The purpose of this study is to evaluate the clinical impact of adjusting phosphorylation analysis in patients with clopidogrel resistance undergoing PCI.

机译：背景：尽管采用双重抗血小板治疗，但经皮冠状动脉介入治疗（PCI）后主要不良心血管事件（MACE）的发生率仍然很高。氯吡格雷抵抗性的离体试验可以预测PCI后的MACE。这项研究的目的是评估在接受PCI的氯吡格雷抵抗性患者中进行磷酸化分析调整的临床效果。

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期刊名称 Clinical Cardiology
作者
Xiao‐dong Wang; Dai‐fu Zhang; Shao‐wei Zhuang; Yan Lai;
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年(卷),期 2011(34),5
年度 2011
页码 332–338
总页数 7
原文格式 PDF
正文语种
中图分类心血管疾病;
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专利

1. Modifying clopidogrel maintenance doses according to vasodilator-stimulated phosphoprotein phosphorylation index improves clinical outcome in patients with clopidogrel resistance. [J] . Wang XD, Zhang DF, Zhuang SW, Clinical cardiology. . 2011,第5期

机译：根据血管扩张剂刺激的磷蛋白磷酸化指数调整氯吡格雷维持剂量可改善氯吡格雷抵抗性患者的临床结局。
2. Modifying Clopidogrel Maintenance Doses According to Vasodilator-Stimulated Phosphoprotein Phosphorylation Index Improves Clinical Outcome in Patients With Clopidogrel Resistance [J] . Xiao-dong Wang MD, Dai-fu Zhang MM, Shao-wei Zhuang MD, Clinical cardiology. . 2011,第5期

机译：根据血管扩张剂刺激的磷酸蛋白磷酸化指数修改氯吡格雷维持剂量可改善氯吡格雷抵抗性患者的临床疗效
3. Adjusted clopidogrel loading doses according to vasodilator-stimulated phosphoprotein phosphorylation index decrease rate of major adverse cardiovascular events in patients with clopidogrel resistance: a multicenter randomized prospective study. [J] . Bonello L, Camoin-Jau L, Arques S, Journal of the American College of Cardiology . 2008,第14期

机译：根据血管扩张剂刺激的磷蛋白磷酸化指数调整氯吡格雷负荷量，可降低氯吡格雷抵抗性患者主要不良心血管事件的发生率：一项多中心随机前瞻性研究。
4. The Vasodilator-Stimulated Phosphoprotein Assay as a Companion Test to Assess P2Y12 Receptor Activity in Clinical Studies [C] . Lisa K. Jennings, Lisa K Jennings, Jayaprakash Kotha Molecular Medicine TRI-CON. . 2014

机译：血管舒张刺激的磷酸蛋白测定作为评估临床研究中P2Y12受体活性的伴随试验
5. Antiplatelet activity to a high loading dose of clopidogrel quantified using point-of-care platelet aggregation assessment, is similar in diabetic versus non-diabetic patients [D] . Nathan, Sandeep 2008

机译：在糖尿病患者和非糖尿病患者中，通过即时护理血小板聚集评估定量的高剂量氯吡格雷抗血小板活性相似
6. Vasodilator-stimulated phosphoprotein-guided Clopidogrel maintenance therapy reduces cardiovascular events in atrial fibrillation patients requiring anticoagulation therapy and scheduled for percutaneous coronary intervention: a prospective cohort study [O] . Chaoyue Hu, Xumin Zhang, Yonghua Liu, 2018

机译：血管扩张剂刺激的磷酸蛋白引导的氯吡格雷维持治疗可减少需要抗凝治疗并计划进行经皮冠状动脉介入治疗的房颤患者的心血管事件：一项前瞻性队列研究
7. Adjusted Clopidogrel Loading Doses According to Vasodilator-Stimulated Phosphoprotein Phosphorylation Index Decrease Rate of Major Adverse Cardiovascular Events in Patients With Clopidogrel Resistance A Multicenter Randomized Prospective Study [O] . Bonello Laurent, Camoin-Jau Laurence, Arques Stéphane, 2008

机译：根据血管扩张剂刺激的磷酸蛋白磷酸化指数降低氯吡格雷耐药性患者主要不良心血管事件发生率的调整氯吡格雷负荷量的多中心随机前瞻性研究

Modifying Clopidogrel Maintenance Doses According to Vasodilator‐Stimulated Phosphoprotein Phosphorylation Index Improves Clinical Outcome in Patients With Clopidogrel Resistance

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