USE OF C4BP-ALPHA PROTEIN IN HUMAN SERUM TO PREDICT CLOPIDOGREL RESISTANCE AND ITS CLINICAL APPLICATION AS A NOVEL BIOMARKER

摘要

The present invention discloses a novel biomarker for predicting clopidogrel resistance and a clinical application thereof. Application of C4BPα protein in human serum as an assay target or standard substance in the preparation of an assay kit for predicting clopidogrel resistance is disclosed. Clinically, the detection of C4BPα in human serum can predict clopidogrel resistance, thereby providing a novel assay for guiding rational use of clopidogrel or drug switching, and helping clinicians to diagnose or predict the clinical efficacy of clopidogrel.