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Unusual Spread of Renal Cell Carcinoma to the Clivus with Cranial Nerve Deficit

机译:肾细胞癌在颅神经缺乏症中不常见地扩散到颅骨

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摘要

Renal cell carcinoma (RCC) has unusual presentation affecting elderly males with a smoking history. The incidence of RCC varies while the incidence of spread of RCC to the clivus is rare. The typicality of RCC presentation includes hematuria, flank pain, and a palpable flank mass; however, RCC can also present with clival metastasis. The unique path of the abducens nerve in the clivus makes it susceptible to damage in metastasis. We report a case of a 54-year-old African American female that was evaluated for back pain, weakness, numbness, and tingling of bilateral lower extremities and subsequently disconjugate gaze and diplopia. Brain MRI confirmed metastasis to the clivus. She was started on radiotherapy and was planned for chemotherapy and transfer to a nursing home. When a patient presents with sudden unusual cranial nerve pathology, the possibility of metastatic RCC should be sought.
机译:肾细胞癌(RCC)具有异常表现,影响有吸烟史的老年男性。 RCC的发生率各不相同,而RCC扩散到锁骨的发生率却很少。 RCC表现的典型性包括血尿,胁腹疼痛和明显的胁腹肿块。但是,RCC也可以出现分支转移。绑架神经在锁骨中的独特路径使其易受转移损伤的影响。我们报告了一例54岁的非洲裔美国女性,该患者经评估背部疼痛,无力,麻木和双侧下肢刺痛,随后解脱凝视和复视。脑部MRI证实已转移至锁骨。她开始接受放射治疗,并计划进行化疗并转移到疗养院。当患者出现突然的异常颅神经病理时,应寻求转移性RCC的可能性。

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