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Retinoblastoma treatment: impact of the glycolytic inhibitor 2-deoxy-d-glucose on molecular genomics expression in LHBETATAG retinal tumors

机译：视网膜母细胞瘤治疗：糖酵解抑制剂2-脱氧-d-葡萄糖对LHBETATAG视网膜肿瘤分子基因组学表达的影响

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摘要

PurposeThe purpose of this study was to evaluate the effect of 2-deoxy-D-glucose (2-DG) on the spatial distribution of the genetic expression of key elements involved in angiogenesis, hypoxia, cellular metabolism, and apoptosis in LHBETATAG retinal tumors.

机译：目的本研究的目的是评估2-脱氧-D-葡萄糖（2-DG）对LHBETATAG视网膜肿瘤中涉及血管生成，缺氧，细胞代谢和细胞凋亡的关键元素遗传表达的空间分布的影响。

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期刊名称 Clinical Ophthalmology (Auckland N.Z.)
作者
Yolanda Piña; Samuel K Houston; Timothy G Murray; Tulay Koru-Sengul; Christina Decatur; William K Scott; Lubov Nathanson; Jennifer Clarke; Theodore J Lampidis;
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作者单位

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年(卷),期 2012(6),-1
年度 2012
页码 817–830
总页数 14
原文格式 PDF
正文语种
中图分类眼科学;
关键词
retinoblastoma hypoxia genetic expression glycolytic inhibitor 2-DG;

机译：视网膜母细胞瘤;缺氧;基因表达;糖酵解抑制剂;2-DG;

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专利

1. Retinoblastoma treatment: impact of the glycolytic inhibitor 2-deoxy-d-glucose on molecular genomics expression in LHBETATAG retinal tumors [J] . Yolanda Pi?a, Samuel K Houston, Timothy G Murray, Clinical ophthalmology . 2012,第8期

机译：视网膜母细胞瘤治疗：糖酵解抑制剂2-脱氧-d-葡萄糖对LHBETATAG视网膜肿瘤分子基因组学表达的影响
2. Retinoblastoma Treatment: Utilization of the Glycolytic Inhibitor, 2-deoxy-2-fluoro-d-glucose (2-FG), to Target the Chemoresistant Hypoxic Regions in LHBETATAG Retinal Tumors [J] . Yolanda Pi?±a, Christina Decatur, Timothy G. Murray, Investigative ophthalmology & visual science . 2012,第2期

机译：视网膜母细胞瘤治疗：利用糖酵解抑制剂2-脱氧-2-氟-d-葡萄糖（2-FG）靶向LHBETATAG视网膜肿瘤中的耐化学性缺氧区域
3. Novel retinoblastoma treatment avoids chemotherapy: the effect of optimally timed combination therapy with angiogenic and glycolytic inhibitors on LHBETATAG retinoblastoma tumors [J] . Samuel K Houston, Yolanda Pi?a, Timothy G Murray, Clinical ophthalmology . 2011,第9期

机译：新型成视网膜细胞瘤治疗可避免化学疗法：最佳时机联合血管生成和糖酵解抑制剂治疗LHBETATAG成视网膜细胞瘤肿瘤的效果
4. Global analysis of protein expression dynamics in human tumor cells upon treatment with the Raf inhibitor Sorafenib [C] . Sven Nahnsen, Oliver Kohlbacher, Alfred Nordheim, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2010

机译：RAF抑制剂Sorafenib治疗后人肿瘤细胞蛋白质表达动力学的全局分析
5. A novel, DNA-based alphavirus gene expression system for rapid recombinant protein purification and virus-based gene delivery to retina and retinoblastoma tumor cells. [D] . DiCiommo, David Patrick. 2002

机译：一种新颖的，基于DNA的α病毒基因表达系统，用于快速重组蛋白纯化和基于病毒的基因传递至视网膜和视网膜母细胞瘤肿瘤细胞。
6. Retinoblastoma Treatment: Utilization of the Glycolytic Inhibitor 2-deoxy-2-fluoro-d-glucose (2-FG) to Target the Chemoresistant Hypoxic Regions in LHBETATAG Retinal Tumors [O] . Yolanda Piña, Christina Decatur, Timothy G. Murray, -1

机译：视网膜母细胞瘤治疗：利用糖酵解抑制剂2-deoxy-2-fluoro-d-glucose（2-FG）靶向LHBETATAG视网膜肿瘤的耐化学性缺氧区域
7. Retinoblastoma treatment: impact of the glycolytic inhibitor 2-deoxy-d-glucose on molecular genomics expression in LHBETATAG retinal tumors [O] . Piña, Yolanda, Houston, Samuel K, Murray, Timothy G, 2012

机译：视网膜母细胞瘤治疗：糖酵解抑制剂2-脱氧-d-葡萄糖对LHBETATAG视网膜肿瘤分子基因组学表达的影响
8. Genomic and Expression Profiling of Benign and Malignant Nerve Sheath Tumors in Neurofibromatosis Patients [R] . Rijn, M. V., Nielsen, T., Rubin, B. 2008

机译：神经纤维瘤病患者良恶性神经鞘瘤的基因组和表达谱分析

Retinoblastoma treatment: impact of the glycolytic inhibitor 2-deoxy-d-glucose on molecular genomics expression in LHBETATAG retinal tumors

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