Metabolomics Investigation of Vitamin a Deficiency in a Rodent Model (P02-016-19)

摘要

ObjectivesVitamin A (VA) is an essential micronutrient with key roles in many biological processes, including growth, vision, reproduction, and immunity. While VA deficiency effects these physiological roles, the impact on many metabolic pathways are poorly studied. Since VA deficiency is a leading cause of morbidity and mortality throughout the world, a more comprehensive understanding of deficiency-associated metabolic alterations is needed. Here we investigate changes in metabolism associated with VA status in a rodent model using targeted metabolomics.