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Data on the clinical usefulness of brachial-ankle pulse wave velocity in patients with suspected coronary artery disease

机译:臂踝脉搏波速度在疑似冠心病患者中的临床实用性数据

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摘要

Brachial-artery pulse wave velocity (baPWV) is a simple and reliable tool for measurement of arterial stiffness. Our previous studies suggested that baPWV is associated with the presence and severity of coronary artery disease (CAD) and the risk of cardiovascular events. In the present data article, we provided supplementary data supporting the independent prognostic value of arterial stiffness, assessed by baPWV, in patients with suspected CAD (Hwang et al., 2017) [1]. The data was obtained from 523 patients undergoing coronary CT angiography (CCTA), and baPWV was measured at the time of CCTA. Patients with vulnerable coronary plaque or obstructive CAD on CCTA had higher age, more cardiovascular risk factors, and higher baPWV values. Given the significant association between high baPWV and the presence of vulnerable plaque or obstructive CAD as shown in this data article, the prognostic value of baPWV was further assessed in subgroups divided according to the CCTA findings (vulnerable plaque or obstructive CAD). In each subgroup by CCTA findings, multivariable Cox proportional hazard model analysis showed that high baPWV was an independent risk factor for cardiovascular events even after adjusting for clinical risk factors.
机译:肱动脉脉搏波速度(baPWV)是一种用于测量动脉僵硬度的简单可靠的工具。我们以前的研究表明,baPWV与冠状动脉疾病(CAD)的存在和严重程度以及心血管事件的风险有关。在本数据文章中,我们提供了补充数据,支持通过baPWV评估的可疑CAD患者的动脉僵硬度的独立预后价值(Hwang等人,2017)[1]。该数据来自523例接受冠状动脉CT血管造影(CCTA)的患者,并且在CCTA时测量了baPWV。 CCTA上易碎的冠状动脉斑块或阻塞性CAD患者的年龄较高,心血管疾病危险因素较高,且baPWV值较高。如本数据文章所述,鉴于高baPWV与易损斑块或阻塞性CAD的存在之间的显着相关性,根据CCTA的发现(易碎斑块或阻塞性CAD)将baPWV的预后价值进一步细分为亚组。根据CCTA的发现,在每个亚组中,多变量Cox比例风险模型分析表明,即使在调整了临床危险因素后,高baPWV仍是心血管事件的独立危险因素。

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