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The role of chemotherapy and prophylactic bilateral oophorectomy in a case of colorectal adenocarcinoma with ovarian metastases.

机译:大肠腺癌伴卵巢转移的化疗和预防性双侧卵巢切除术的作用。

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摘要

A 66-year-old female presented with a large abdominal mass and accompanying systemic complaints of abdominal pain, constipation. and fever. On exploratory laparotomy, the mass was found to be a moderately differentiated adenocarcinoma of the sigmoid colon with metastasis to the left ovary. A primary colorectal carcinoma that has metastasized to the ovaries can be difficult to distinguish clinically from an advanced primary ovarian tumor. Histology and tumor markers are currently the most useful tools available in making an accurate diagnosis. If the nature of the primary tumor is uncertain and the initial response to chemotherapy is poor, the patient's prognosis will also he poor. Though controversy exists regarding the role of prophylactic bilateral oophorectomy during resection for primary colorectal cancer, later confusion can be avoided by performing this procedure when the colorectal carcinoma is first diagnosed. However the possibility of a concurrent primary ovarian tumor must not be overlooked.
机译:一位66岁的女性,腹部大肿块,伴有腹部疼痛,便秘的全身症状。和发烧。在探索性剖腹手术中,发现该肿物是乙状结肠的中度分化腺癌,转移至左卵巢。已经转移到卵巢的原发性大肠癌在临床上可能很难与晚期原发性卵巢肿瘤区分开。组织学和肿瘤标志物是目前进行准确诊断最有用的工具。如果原发性肿瘤的性质不确定并且对化学疗法的初始反应较差,则患者的预后也会较差。尽管对于原发性大肠癌的切除术中预防性双侧卵巢切除术的作用存在争议,但是当首次诊断为大肠癌时,可以通过执行此程序避免以后的混淆。然而,并发原发性卵巢肿瘤的可能性一定不能忽视。

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