Effect of environmental salinity on expression of adrenomedullin genes suggests osmoregulatory activity in the medaka Oryzias latipes

摘要

IntroductionThe adrenomedullins (AMs) comprise a hormonal family in mammals and teleost fishes, with five members (AM1–5) found or predicted in most of the teleosts including Japanese medaka (Oryzias latipes). AM1 is known to have cardiovascular and osmoregulatory functions in mammals, but the roles of most AMs are yet to be determined.