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When are the BET factors the most sensitive to bromodomain inhibitors?

机译：BET因子何时对溴结构域抑制剂最敏感？

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The recent publication of two detailed studies of mouse spermatogenesis, either after chemical inhibition of the BET bromodomains, or in the context of genetic alterations of one specific BET member, Brdt, provides the unique opportunity to assess the functional impact of BET bromodomain inhibitors.

机译：最近对小鼠精子发生的两项详细研究的最新发表，无论是在化学抑制BET溴结构域之后，还是在一个特定BET成员Brdt的遗传改变的背景下，都提供了独特的机会来评估BET溴结构域抑制剂的功能影响。

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期刊名称 Transcription
作者
Saadi Khochbin;
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年(卷),期 2013(4),2
年度 2013
页码 54–57
总页数 4
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1. When are the BET factors the most sensitive to bromodomain inhibitors? [J] . Saadi Khochbin Transcription . 2013,第2期

机译：BET因子何时对溴结构域抑制剂最敏感？
2. Identification of a novel BET bromodomain inhibitor‐sensitive, gene regulatory circuit that controls Rituximab response and tumour growth in aggressive lymphoid cancers [J] . Alexandra Debernardi, Anouk Emadali, Benoit Bernay, EMBO Molecular Medicine . 2013,第8期

机译：鉴定新型BET溴结构域抑制剂敏感的基因调控电路，该电路可控制利妥昔单抗反应和侵袭性淋巴癌中的肿瘤生长
3. The homeobox transcription factor MEIS2 is a regulator of cancer cell survival and IMiDs activity in Multiple Myeloma: modulation by Bromodomain and Extra-Terminal (BET) protein inhibitors [J] . Maria Pia Abruzzese, Maria Teresa Bilotta, Cinzia Fionda, Cell death & disease. . 2019,第4期

机译：Homeobox转录因子Meis2是多发性骨髓瘤中的癌细胞存活和IMIDS活性的调节因子：由溴琼瘤和外终端（BET）蛋白质抑制剂的调节
4. ANALYSIS OF THE BROMODOMAIN BRD3 AND ITS INTERACTIONS WITH THE INHIBITOR JQ1 [C] . William B. Smith, Sean R. Marcsisin, Panagis Filippakopoulos, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2012

机译：溴琼素BRD3分析及其与抑制剂JQ1的相互作用
5. Development of Nano-Liposomal Formulations of Epidermal Growth Factor Receptor Inhibitors and their Pharmacological Interactions on Drug-Sensitive and Drug-Resistant Cancer Cell Lines. [D] . Trummer, Brian J. 2010

机译：表皮生长因子受体抑制剂的纳米脂质体制剂的开发及其在药物敏感性和耐药性癌细胞系上的药理相互作用。
6. Identification of a novel BET bromodomain inhibitor-sensitive gene regulatory circuit that controls Rituximab response and tumour growth in aggressive lymphoid cancers [O] . Anouk Emadali, Sophie Rousseaux, Juliana Bruder-Costa, 2013

机译：确定新型BET溴结构域抑制剂敏感的基因调控电路该电路可控制利妥昔单抗反应和侵袭性淋巴癌中的肿瘤生长
7. Identification of a novel BET bromodomain inhibitor-sensitive, gene regulatory circuit that controls Rituximab response and tumour growth in aggressive lymphoid cancers. : CYCLON-induced Rituximab resistance [O] . Emadali, Anouk, Rousseaux, Sophie, Bruder-Costa, Juliana, 2013

机译：确定了新型BET溴结构域抑制剂敏感的基因调节电路，该电路可控制利妥昔单抗反应和侵袭性淋巴癌中的肿瘤生长。：CYCLON诱导的利妥昔单抗耐药

When are the BET factors the most sensitive to bromodomain inhibitors?

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