AMPLIFYING BETA CELL DIFFERENTIATION WITH SMALL MOLECULES BET (BROMODOMAIN AND EXTRATERMINAL FAMILY OF BROMODOMAIN-CONTAINING PROTEINS) INHIBITORS

摘要

The present invention provides an in vitromethod for obtaining cells of the pancreatic endocrine lineage, comprising a step of culturing pancreatic progenitor cells, wherein said pancreatic progenitor cells are in a cell culture medium comprising at least one BET inhibitor.